A1VE58 (A1VE58_DESVV) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ABM28724.1
EC=2.4.1.182 EMBL ABM28724.1

Gene names

Ordered Locus Names:

Dvul_1707

Organism

Desulfovibrio vulgaris subsp. vulgaris (strain DP4) [Complete proteome] [HAMAP]

Taxonomic identifier

391774 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ABM28724.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1VE58 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 962CEAB6499527A6	FASTA	376	41,580
	10 20 30 40 50 60 MPPSIWINTG ELSGDMHGAA LLEALRALAP DLSCTGMGGP YLRAAGQQAM LRVEDLSVMG 70 80 90 100 110 120 ITEVIAYLPR IFSMLRDIRA ELARTRPDAV VLIDAPEFNF RVAKAATDLG IPVYYYISPK 130 140 150 160 170 180 IWAWRTGRVQ FIKRHVRRML SILPFEVDFY RRHGMEVDYV GNPLVDMVDW PALAAIAPVE 190 200 210 220 230 240 GRIGLMPGSR RKEVESLMPA FGDAARLMLE HRPGLDFHCM RAPSTTEAAL RALWPQDIPL 250 260 270 280 290 300 HIVAPEDRYH AVRSCQMLIA ASGTATLETA LIGTPTLVTY KVSPFSYWLG RKLVKVRFAA 310 320 330 340 350 360 LPNLVLDREV FPELLQEKAT GPVIAQHAAA WLDAPEALAA VRSELDVLRT MLGEPGAAGR 370 AARIIIDDLT GRKQQD

References

[1]

"Contribution of mobile genetic elements to Desulfovibrio vulgaris genome plasticity." Walker C.B., Stolyar S., Chivian D., Pinel N., Gabster J.A., Dehal P.S., He Z., Yang Z.K., Yen H.C., Zhou J., Wall J.D., Hazen T.C., Arkin A.P., Stahl D.A. Environ. Microbiol. 11:2244-2252(2009) [PubMed: 19737303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000527 Genomic DNA. Translation: ABM28724.1.
RefSeq	YP_967151.1. NC_008751.1.
3D structure databases
ProteinModelPortal	A1VE58.
ModBase	Search...
Protein-protein interaction databases
STRING	A1VE58.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4663396.
GenomeReviews	Gene locus Dvul_1707 in contig CP000527_GR.
KEGG	dvl:Dvul_1707.
NMPDR	fig|391774.5.peg.1705.
PATRIC	21767290. VBIDesVul62463_1920.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	AEFAFIC.
PhylomeDB	A1VE58.
ProtClustDB	CLSK705191.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1VE58_DESVV

Accession

Primary (citable) accession number: A1VE58

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)