Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Succinyl-CoA ligase [ADP-forming] subunit alpha

Gene

Dvul_1095

Organism
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP citrate synthase activity Source: InterPro
  3. cofactor binding Source: InterPro
  4. succinate-CoA ligase (ADP-forming) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciDVUL391774:GHS0-1135-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Succinyl-CoA ligase [ADP-forming] subunit alphaUniRule annotation (EC:6.2.1.5UniRule annotation)
Gene namesi
Ordered Locus Names:Dvul_1095Imported
OrganismiDesulfovibrio vulgaris subsp. vulgaris (strain DP4)Imported
Taxonomic identifieri391774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000009173: Chromosome

Interactioni

Subunit structurei

Heterotetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi391774.Dvul_1095.

Structurei

3D structure databases

ProteinModelPortaliA1VCE9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the succinate/malate CoA ligase alpha subunit family.UniRule annotation
Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0045.
HOGENOMiHOG000227941.
KOiK01902.
OMAiDSVHEAC.
OrthoDBiEOG644ZT0.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.261. 2 hits.
3.40.50.720. 1 hit.
InterProiIPR013650. ATP-grasp_succ-CoA_synth-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF08442. ATP-grasp_2. 1 hit.
PF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 2 hits.
[Graphical view]
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF52210. SSF52210. 2 hits.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1VCE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLNEHQSKR LFEEAGIETP QGIMTDSAGI EGCLPPFDAP WFVKAQVLAG
60 70 80 90 100
GRGKAGGVRR ADDLAGLRDV AKDILGMRIG GHAVPFVRIE PATAIARECY
110 120 130 140 150
VSFMVSRKRR ELLFTASGSG GVEVESGQGA LVRAVPLTGE MPEHVIRSAF
160 170 180 190 200
FCTGVGREHW AGFREFVLRL HGAVRDYGLL LAEVNPLVLT GDGRWLALDG
210 220 230 240 250
KVEVDDNVVD IRPDLLRFHT PEHLAPEENA AREAGLSYVE LKGWVGLLVN
260 270 280 290 300
GAGLAMATMD LLNFSGLAAA NFMDLGGAAD VPRMRRALEL LFGNPQVRVV
310 320 330 340 350
CVNLFGGIVS CAAVAGALVE ALGDGRAAKP VVVRMDGFEA AEGRQLLERR
360 370 380 390 400
AHPDVHVARD IDHALDLLRH LRPADAPDIV FTPGTEKPVP RIHGGAAGTR
410 420 430 440 450
RGTPHLGKGA RVLVQGITGR SAQLHTRLML DYGTNIVAGV TPFKGGQVTQ
460 470 480 490 500
GVPVYDSVHE ACRQHDIDAT ILFVPAAFAA DSLLEAVAEG IPWAVCITEG
510 520 530 540 550
IPQKDMLRAL RVARGARTRI IGPNTPGIIV PGACKVGIMP GNVFSPGPLA
560 570 580 590 600
VFSRSGTLTY EAAARLSAAG IGQSLCAGVG GDPYIGSDFV SLCELVRDDE
610 620 630 640 650
ATQGVLVLGE VGGTAEEELA AWVRETAFPK PVVSFVAGRT APPGRRLGHA
660 670 680 690
GAILDEADGG IAGKVRALCD AGIAVCPDLG SLPAAVRQAL R
Length:691
Mass (Da):72,786
Last modified:February 6, 2007 - v1
Checksum:iEB4B7E1F134E3C95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000527 Genomic DNA. Translation: ABM28115.1.
RefSeqiYP_966542.1. NC_008751.1.

Genome annotation databases

EnsemblBacteriaiABM28115; ABM28115; Dvul_1095.
GeneIDi4662928.
KEGGidvl:Dvul_1095.
PATRICi21765993. VBIDesVul62463_1285.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000527 Genomic DNA. Translation: ABM28115.1.
RefSeqiYP_966542.1. NC_008751.1.

3D structure databases

ProteinModelPortaliA1VCE9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi391774.Dvul_1095.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM28115; ABM28115; Dvul_1095.
GeneIDi4662928.
KEGGidvl:Dvul_1095.
PATRICi21765993. VBIDesVul62463_1285.

Phylogenomic databases

eggNOGiCOG0045.
HOGENOMiHOG000227941.
KOiK01902.
OMAiDSVHEAC.
OrthoDBiEOG644ZT0.

Enzyme and pathway databases

BioCyciDVUL391774:GHS0-1135-MONOMER.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.261. 2 hits.
3.40.50.720. 1 hit.
InterProiIPR013650. ATP-grasp_succ-CoA_synth-type.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR017440. Cit_synth/succinyl-CoA_lig_AS.
IPR003781. CoA-bd.
IPR005810. CoA_lig_alpha.
IPR005811. CoA_ligase.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF08442. ATP-grasp_2. 1 hit.
PF02629. CoA_binding. 1 hit.
PF00549. Ligase_CoA. 2 hits.
[Graphical view]
PRINTSiPR01798. SCOASYNTHASE.
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF52210. SSF52210. 2 hits.
TIGRFAMsiTIGR01019. sucCoAalpha. 1 hit.
PROSITEiPS00399. SUCCINYL_COA_LIG_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DP4Imported.

Entry informationi

Entry nameiA1VCE9_DESVV
AccessioniPrimary (citable) accession number: A1VCE9
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: March 4, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.