A1VBD0 (A1VBD0_DESVV) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate kinase HAMAP-Rule MF_00109
Short name=SK HAMAP-Rule MF_00109
EC=2.7.1.71 HAMAP-Rule MF_00109

Gene names

Name:	aroK HAMAP-Rule MF_00109
Ordered Locus Names:	Dvul_0723 EMBL ABM27746.1

Organism

Desulfovibrio vulgaris subsp. vulgaris (strain DP4) [Complete proteome] [HAMAP] EMBL ABM27746.1

Taxonomic identifier

391774 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio › Desulfovibrio vulgaris

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity. HAMAP-Rule MF_00109
Catalytic activity	ATP + shikimate = ADP + shikimate 3-phosphate. HAMAP-Rule MF_00109
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_00109
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. HAMAP-Rule MF_00109
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00109
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00109.
Sequence similarities	Belongs to the shikimate kinase family. HAMAP-Rule MF_00109

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP-Rule MF_00109
Cellular component	Cytoplasm HAMAP-Rule MF_00109
Ligand	ATP-binding HAMAP-Rule MF_00109 Magnesium HAMAP-Rule MF_00109 Metal-binding HAMAP-Rule MF_00109 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00109 EMBL ABM27746.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP chorismate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP shikimate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	23 – 28	6	ATP By similarity HAMAP-Rule MF_00109
Sites
	Metal binding	27	1	Magnesium By similarity HAMAP-Rule MF_00109
	Binding site	45	1	Substrate By similarity HAMAP-Rule MF_00109
	Binding site	90	1	Substrate; via amide nitrogen By similarity HAMAP-Rule MF_00109
	Binding site	128	1	ATP By similarity HAMAP-Rule MF_00109
	Binding site	145	1	Substrate By similarity HAMAP-Rule MF_00109

Sequences

	Sequence		Length	Mass (Da)
	A1VBD0 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: E6D5E6123780A1E6	FASTA	180	19,615
	10 20 30 40 50 60 MMTRREGARL FEGCCVTIIG MAGAGKTTVG RELARQMDWA HVDTDSLIEA TYGTVLQNVA 70 80 90 100 110 120 DSMSKEAFLD VEAGIICRIG AKRAVLSTGG SVVYRAEAMR HLASLGPVVY LDVSLPLILE 130 140 150 160 170 180 RIARNPDRGL AIAPGQTIED LYNERKALYE TYQDFTLTAD TLTPEECGRA ILSWLETADA

References

[1]

"Contribution of mobile genetic elements to Desulfovibrio vulgaris genome plasticity." Walker C.B., Stolyar S., Chivian D., Pinel N., Gabster J.A., Dehal P.S., He Z., Yang Z.K., Yen H.C., Zhou J., Wall J.D., Hazen T.C., Arkin A.P., Stahl D.A. Environ. Microbiol. 11:2244-2252(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DP4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000527 Genomic DNA. Translation: ABM27746.1.
RefSeq	YP_966173.1. NC_008751.1.
3D structure databases
ProteinModelPortal	A1VBD0.
ModBase	Search...
Protein-protein interaction databases
STRING	391774.Dvul_0723.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABM27746; ABM27746; Dvul_0723.
GeneID	4662778.
KEGG	dvl:Dvul_0723.
PATRIC	21765213. VBIDesVul62463_0910.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0703.
HOGENOM	HOG000032568.
KO	K00891.
OMA	VYGKEAM.
ProtClustDB	PRK00131.
Enzyme and pathway databases
BioCyc	DVUL391774:GHS0-810-MONOMER.
UniPathway	UPA00053; UER00088.
Family and domain databases
HAMAP	MF_00109. Shikimate_kinase.
InterPro	IPR000623. Shikimate_kinase. [Graphical view]
Pfam	PF01202. SKI. 1 hit. [Graphical view]
PRINTS	PR01100. SHIKIMTKNASE.
ProtoNet	Search...

Entry information

Entry name

A1VBD0_DESVV

Accession

Primary (citable) accession number: A1VBD0

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)