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A1VBD0

- A1VBD0_DESVV

UniProt

A1VBD0 - A1VBD0_DESVV

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Protein
Shikimate kinase
Gene
aroK, Dvul_0723
Organism
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity.UniRule annotation

Catalytic activityi

ATP + shikimate = ADP + shikimate 3-phosphate.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi27 – 271Magnesium By similarityUniRule annotation
Binding sitei45 – 451Substrate By similarityUniRule annotation
Binding sitei90 – 901Substrate; via amide nitrogen By similarityUniRule annotation
Binding sitei128 – 1281ATP By similarityUniRule annotation
Binding sitei145 – 1451Substrate By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi23 – 286ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. shikimate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. aromatic amino acid family biosynthetic process Source: UniProtKB-HAMAP
  2. chorismate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciDVUL391774:GHS0-749-MONOMER.
UniPathwayiUPA00053; UER00088.

Names & Taxonomyi

Protein namesi
Recommended name:
Shikimate kinaseUniRule annotation (EC:2.7.1.71UniRule annotation)
Short name:
SKUniRule annotation
Gene namesi
Name:aroKUniRule annotation
Ordered Locus Names:Dvul_0723Imported
OrganismiDesulfovibrio vulgaris subsp. vulgaris (strain DP4)Imported
Taxonomic identifieri391774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000009173: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi391774.Dvul_0723.

Structurei

3D structure databases

ProteinModelPortaliA1VBD0.

Family & Domainsi

Sequence similaritiesi

Belongs to the shikimate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0703.
HOGENOMiHOG000032568.
KOiK00891.
OMAiVYGKEAM.
OrthoDBiEOG6SJJGD.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00109. Shikimate_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR000623. Shikimate_kinase/TSH1.
[Graphical view]
PfamiPF01202. SKI. 1 hit.
[Graphical view]
PRINTSiPR01100. SHIKIMTKNASE.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A1VBD0-1 [UniParc]FASTAAdd to Basket

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MMTRREGARL FEGCCVTIIG MAGAGKTTVG RELARQMDWA HVDTDSLIEA    50
TYGTVLQNVA DSMSKEAFLD VEAGIICRIG AKRAVLSTGG SVVYRAEAMR 100
HLASLGPVVY LDVSLPLILE RIARNPDRGL AIAPGQTIED LYNERKALYE 150
TYQDFTLTAD TLTPEECGRA ILSWLETADA 180
Length:180
Mass (Da):19,615
Last modified:February 6, 2007 - v1
Checksum:iE6D5E6123780A1E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000527 Genomic DNA. Translation: ABM27746.1.
RefSeqiWP_010939791.1. NC_008751.1.
YP_966173.1. NC_008751.1.

Genome annotation databases

EnsemblBacteriaiABM27746; ABM27746; Dvul_0723.
GeneIDi4662778.
KEGGidvl:Dvul_0723.
PATRICi21765213. VBIDesVul62463_0910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000527 Genomic DNA. Translation: ABM27746.1 .
RefSeqi WP_010939791.1. NC_008751.1.
YP_966173.1. NC_008751.1.

3D structure databases

ProteinModelPortali A1VBD0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 391774.Dvul_0723.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM27746 ; ABM27746 ; Dvul_0723 .
GeneIDi 4662778.
KEGGi dvl:Dvul_0723.
PATRICi 21765213. VBIDesVul62463_0910.

Phylogenomic databases

eggNOGi COG0703.
HOGENOMi HOG000032568.
KOi K00891.
OMAi VYGKEAM.
OrthoDBi EOG6SJJGD.

Enzyme and pathway databases

UniPathwayi UPA00053 ; UER00088 .
BioCyci DVUL391774:GHS0-749-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00109. Shikimate_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR000623. Shikimate_kinase/TSH1.
[Graphical view ]
Pfami PF01202. SKI. 1 hit.
[Graphical view ]
PRINTSi PR01100. SHIKIMTKNASE.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DP4.

Entry informationi

Entry nameiA1VBD0_DESVV
AccessioniPrimary (citable) accession number: A1VBD0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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