A1VAA0 (ACKA_DESVV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase
EC=2.7.2.1

Alternative name(s):
Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	Dvul_0343

Organism

Desulfovibrio vulgaris subsp. vulgaris (strain DP4) [Complete proteome] [HAMAP]

Taxonomic identifier

391774 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	402 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 402	402	Acetate kinase HAMAP MF_00020		PRO_1000002230

Sequences

	Sequence		Length	Mass (Da)
	A1VAA0 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 3EF1D601CB4E62F7	FASTA	402	44,104
	10 20 30 40 50 60 MNVLVINSGS SSIKYQLIDM EREVPLCSGL VERIGEPMGK LTHKIRPDAE GEEKLTFEQP 70 80 90 100 110 120 FTNHVEGMKR VVELITDADK GVIKDKSEIG AIGHRVLLGG EEIKQSVRID DWAKGVIRDY 130 140 150 160 170 180 IPLGPLHNPA NLAGIEVAEE LFPGLPNVGV FDTEFHQSMP AKAYLYPLPI ELYEELKIRR 190 200 210 220 230 240 YGFHGTSHRY ITKRTAQYLG KPLDELNIIT CHLGNGCSMA AVKNGKCVDT TMGITPLEGL 250 260 270 280 290 300 MMGTRCGDID PAIVPFLMEK KNLSPAEADT LMNKQSGLKG VCGMNDMRDL HAARENGNER 310 320 330 340 350 360 AQLAFEMFTY RIKKYIGAYY AVLGRVDAVV FTAGIGENDD FVRAEVCAGL DSLGIAVDPA 370 380 390 400 RNAVRNGQPR HISPDGSRVA VLVVPTNEEL EIAQATLDVL KG

References

[1]

"Contribution of mobile genetic elements to Desulfovibrio vulgaris genome plasticity." Walker C.B., Stolyar S., Chivian D., Pinel N., Gabster J.A., Dehal P.S., He Z., Yang Z.K., Yen H.C., Zhou J., Wall J.D., Hazen T.C., Arkin A.P., Stahl D.A. Environ. Microbiol. 11:2244-2252(2009) [PubMed: 19737303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DP4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000527 Genomic DNA. Translation: ABM27366.1.
RefSeq	YP_965793.1. NC_008751.1.
3D structure databases
ProteinModelPortal	A1VAA0.
SMR	A1VAA0. Positions 1-401.
ModBase	Search...
Protein-protein interaction databases
STRING	A1VAA0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4662591.
GenomeReviews	Gene locus Dvul_0343 in contig CP000527_GR.
KEGG	dvl:Dvul_0343.
NMPDR	fig|391774.5.peg.462.
PATRIC	21764375. VBIDesVul62463_0507.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	SHAYVSR.
PhylomeDB	A1VAA0.
ProtClustDB	PRK00180.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_DESVV

Accession

Primary (citable) accession number: A1VAA0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program