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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:Dvul_0030
OrganismiDesulfovibrio vulgaris subsp. vulgaris (strain DP4)
Taxonomic identifieri391774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000009173 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000200541 – 330Methionyl-tRNA formyltransferaseAdd BLAST330

Proteomic databases

PRIDEiA1V9B4

Structurei

3D structure databases

ProteinModelPortaliA1V9B4
SMRiA1V9B4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni116 – 119Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
IPR001555 GART_AS
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit
PROSITEiView protein in PROSITE
PS00373 GART, 1 hit

Sequencei

Sequence statusi: Complete.

A1V9B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAESAPLKIV FMGTPDFAAA SLRHLLAWDG CDVVGVYTQP DRPCGRGQQC
60 70 80 90 100
RPSAVKMLAL EHGLDVRQPV NFRDEADVQA LRDFGADILV VAAYGLILPQ
110 120 130 140 150
SVLDAAPMGA VNVHGSLLPR YRGAAPIQRA VMNGDAVTGI TIMQVVKQLD
160 170 180 190 200
AGPMLLQKAL GIGCDETSGQ LHDQLAELGG RLLVETLARL RAGTIMPIPQ
210 220 230 240 250
DDALATYAAK LTKADGLVDW NRTAVEVHAQ VRGVTPWPAA YFTLRREGQK
260 270 280 290 300
DVRVTIEPGT IGPLLEQPAV PGTIVGLVDG AIAFACADRT YLVRTIRPAD
310 320 330
KKPMTGEAFW CGYLSRCEGE CPGFAVCEGA
Length:330
Mass (Da):35,224
Last modified:February 6, 2007 - v1
Checksum:iF39C4FD13D85ECC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000527 Genomic DNA Translation: ABM27054.1
RefSeqiWP_011791337.1, NC_008751.1

Genome annotation databases

EnsemblBacteriaiABM27054; ABM27054; Dvul_0030
KEGGidvl:Dvul_0030

Similar proteinsi

Entry informationi

Entry nameiFMT_DESVV
AccessioniPrimary (citable) accession number: A1V9B4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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