A1V5C1 (A1V5C1_BURMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Name:	fabI EMBL ABM51313.1
Ordered Locus Names:	BMASAVP1_A2111

Organism

Burkholderia mallei (strain SAVP1) [Complete proteome] [HAMAP]

Taxonomic identifier

320388 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL ABM51313.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	156	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	A1V5C1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: BEE6B7EDC0290628	FASTA	263	27,771
	10 20 30 40 50 60 MGFLDGKRIL LTGLLSNRSI AYGIAKACKR EGAELAFTYV GDRFKDRITE FAAEFGSELV 70 80 90 100 110 120 FPCDVADDAQ IDALFASLKT HWDSLDGLVH SIGFAPREAI AGDFLDGLTR ENFRIAHDIS 130 140 150 160 170 180 AYSFPALAKA ALPMLSDDAS LLTLSYLGAE RAIPNYNTMG LAKAALEASV RYLAVSLGAK 190 200 210 220 230 240 GVRVNAISAG PIKTLAASGI KSFGKILDFV ESNSPLKRNV TIEQVGNAGA FLLSDLASGV 250 260 TAEVMHVDSG FNAVVGGMAG LEE

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000526 Genomic DNA. Translation: ABM51313.1.
RefSeq	YP_993424.1. NC_008785.1.
3D structure databases
ProteinModelPortal	A1V5C1.
SMR	A1V5C1. Positions 2-262.
ModBase	Search...
Protein-protein interaction databases
STRING	A1V5C1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4681132.
GenomeReviews	Gene locus BMASAVP1_A2111 in contig CP000526_GR.
KEGG	bmv:BMASAVP1_A2111.
PATRIC	19156947. VBIBurMal134057_3718.
TIGR	BMASAVP1_A2111.
Phylogenomic databases
HOGENOM	HBG750976.
OMA	KKWDGLD.
ProtClustDB	PRK06997.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

A1V5C1_BURMS

Accession

Primary (citable) accession number: A1V5C1

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)