Reviewed, UniProtKB/Swiss-Prot A1V2K3 (PSD_BURMS)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	BMASAVP1_A1116

Organism

Burkholderia mallei (strain SAVP1) [Complete proteome] [HAMAP]

Taxonomic identifier

320388 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	216 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity.
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 181	181	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000026638
	Chain	182 – 216	35	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000026639
Sites
	Site	181 – 182	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	182	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1V2K3-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: B1F9517AA99A232F	FASTA	216	23,462
	10 20 30 40 50 60 MNYPHPIIAR EGWPFIAIAA VVALLIHAVG GFGLAWPFWL LLVFVVQFFR DPPRAVPTQA 70 80 90 100 110 120 NAVLCPADGR IVAVETAHDP YADREALKIS VFMNVFNVHS QRSPVDGAVQ KVEYFPGAFL 130 140 150 160 170 180 NAALDKASAE NERNAVVIQT GAGHTVTAVQ IAGLVARRIL CYVRAGEPLS RGQRYGFIRF 190 200 210 GSRVDVYLPK GSRARVSIGE KVSASSTILA ELPEQP

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000526 Genomic DNA. Translation: ABM51489.1.
RefSeq	YP_992456.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4679043.
GenomeReviews	Gene locus BMASAVP1_A1116 in contig CP000526_GR.
KEGG	bmv:BMASAVP1_A1116.
TIGR	BMASAVP1_A1116.
Phylogenomic databases
OMA	DKASEDN.
Family and domain databases
HAMAP	MF_00664. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase_related. [Graphical view]
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_BURMS

Accession

Primary (citable) accession number: A1V2K3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)