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A1V1I6 (A1V1I6_BURMS) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA (guanine-N(7)-)-methyltransferase HAMAP-Rule MF_01057
EC=2.1.1.33 HAMAP-Rule MF_01057
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase HAMAP-Rule MF_01057
tRNA(m7G46)-methyltransferase HAMAP-Rule MF_01057
Gene names
Name:trmB HAMAP-Rule MF_01057 EMBL ABM49924.1
Ordered Locus Names:BMASAVP1_A0743
OrganismBurkholderia mallei (strain SAVP1) [Complete proteome] [HAMAP]
Taxonomic identifier320388 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group ›

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity. HAMAP-Rule MF_01057

Catalytic activity

S-adenosyl-L-methionine + guanine46 in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine46 in tRNA. HAMAP-Rule MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP-Rule MF_01057

Sequence similarities

Belongs to the methyltransferase superfamily. TrmB family. HAMAP-Rule MF_01057

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region240 – 2434Substrate binding By similarity HAMAP-Rule MF_01057

Sites

Binding site941S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1191S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1461S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1691S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1731Substrate By similarity HAMAP-Rule MF_01057
Binding site2051Substrate By similarity HAMAP-Rule MF_01057

Sequences

Sequence LengthMass (Da)Tools
A1V1I6 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: ABA972FFA4374B2F

FASTA26428,986
        10         20         30         40         50         60 
MIHDDDPNAP GAPHDDATAA PASATRAAPA AGDDDDANPL HLRRIRSFVT RAGRVSTGQR 

        70         80         90        100        110        120 
RAIDELGPRF VIPYGSAQPD WDAIFGRRAP RVLEIGFGMG ASTAEIAALR PGDDFIGVEV 

       130        140        150        160        170        180 
HEPGVGALLK LIGEQQLSNI RIIQHDAVEV LAQMIAPDSL DGVHIFFPDP WHKARHHKRR 

       190        200        210        220        230        240 
LIQPPFVAQL AAHLKPGAYL HCATDWQNYA EQMLEVLSAD PSLENTAQNY APRPGYRPVT 

       250        260 
KFERRGLRLG HGVWDLVFRK KHAG

« Hide

References

[1]DeShazer D., Woods D.E., Nierman W.C.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SAVP1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000526 Genomic DNA. Translation: ABM49924.1.
RefSeqYP_992089.1. NC_008785.1.

3D structure databases

ProteinModelPortalA1V1I6.
ModBaseSearch...

Protein-protein interaction databases

STRING320388.BMASAVP1_A0743.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM49924; ABM49924; BMASAVP1_A0743.
GeneID4679721.
KEGGbmv:BMASAVP1_A0743.
PATRIC19154234. VBIBurMal134057_2384.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0220.
HOGENOMHOG000073968.
KOK03439.
OMACEVHEPG.
ProtClustDBPRK00121.

Enzyme and pathway databases

BioCycBMAL320388:GHFL-791-MONOMER.
UniPathwayUPA00989.

Family and domain databases

HAMAPMF_01057. tRNA_methyltr_TrmB.
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. TIGR00091. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1V1I6_BURMS
AccessionPrimary (citable) accession number: A1V1I6
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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