A1V0L1 (A1V0L1_BURMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase 2 HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE EMBL ABM51040.1
Synonyms:	aroE2 HAMAP MF_00222
Ordered Locus Names:	BMASAVP1_A0414

Organism

Burkholderia mallei (strain SAVP1) [Complete proteome] [HAMAP]

Taxonomic identifier

320388 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222 SAAS SAAS011342
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222 SAAS SAAS011342
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222 SAAS SAAS011342
Ligand	NADP HAMAP MF_00222 SAAS SAAS011342
Molecular function	Oxidoreductase HAMAP MF_00222 RuleBase RU004037 SAAS SAAS011342 EMBL ABM51040.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	137 – 141	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	76	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	A1V0L1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 1FC4AA40A1940D77	FASTA	292	30,004
	10 20 30 40 50 60 MSTAVESAAR ARDRYAVIGN PIAHSKSPFI HSRFAEQTGE AIEYTHLLAP LDGFSATVRA 70 80 90 100 110 120 FIAQGGRGVN VTVPFKLEAY ALADALSPRA AAAGAVNTLR FDADGVFGDN TDGVGLVRDI 130 140 150 160 170 180 EVNLGVSLTG ARILLLGAGG AARGVVLPML ERGPASLTIV NRTASKAEEL VGQFTQAAHD 190 200 210 220 230 240 AGCVLAGGGP ERIAREPYDV IVNATAGSLD AALPECDAAA FGPATLAYDM MYGARPTVFM 250 260 270 280 290 EHAAALGART ADGLGMLVEQ AAESFHVWRG VRPDSAPVLA ALRAALAASA AH

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000526 Genomic DNA. Translation: ABM51040.1.
RefSeq	YP_991764.1. NC_008785.1.
3D structure databases
ProteinModelPortal	A1V0L1.
ModBase	Search...
Protein-protein interaction databases
STRING	A1V0L1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4679315.
GenomeReviews	Gene locus BMASAVP1_A0414 in contig CP000526_GR.
KEGG	bmv:BMASAVP1_A0414.
PATRIC	19153572. VBIBurMal134057_2055.
TIGR	BMASAVP1_A0414.
Phylogenomic databases
HOGENOM	HBG553408.
OMA	VVFGNPI.
ProtClustDB	PRK00258.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. IPR006151. Shikm_DH/Glu-tRNA_Rdtase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF01488. Shikimate_DH. 1 hit. PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1V0L1_BURMS

Accession

Primary (citable) accession number: A1V0L1

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)