A1UZE3 (A1UZE3_BURMS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase 1 HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE1 HAMAP MF_00222
Ordered Locus Names:	BMASAVP1_1754

Organism

Burkholderia mallei (strain SAVP1) [Complete proteome] [HAMAP] EMBL ABM48975.1

Taxonomic identifier

320388 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222
Ligand	NADP HAMAP MF_00222
Molecular function	Oxidoreductase HAMAP MF_00222
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	134 – 138	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	74	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	A1UZE3 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: B6C53E2D4F3EE1E5	FASTA	284	29,783
	10 20 30 40 50 60 MSGRSFLIGL IGAGIGGSLS PAMHEAEGRR QGLNYVYRRI DLDALGLTAD ALPELLATAE 70 80 90 100 110 120 RMGFDGLNIT HPCKQRVIEH LDELSADAAA LGAVNTVCFA HGRRIGHNTD WSGFAKAFAR 130 140 150 160 170 180 GLPGASLERV VQLGAGGAGA AVAHAALTMG AAQLALFDVD PVRARSLADQ LQARFPHARL 190 200 210 220 230 240 SAGGTLADAL ANATGLIHAT PTGMLGHPGL PLPAHLLRSG LWVADIVYFP LETELIRAAR 250 260 270 280 ALGCRTLPGG GMAVYQAVDA FELFTGRAPD AERMFEHFRA LVAR

References

[1]	DeShazer D., Woods D.E., Nierman W.C. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: SAVP1 EMBL ABM48975.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000525 Genomic DNA. Translation: ABM48975.1.
RefSeq	YP_991346.1. NC_008784.1.
3D structure databases
ProteinModelPortal	A1UZE3.
ModBase	Search...
Protein-protein interaction databases
STRING	A1UZE3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4677959.
GenomeReviews	Gene locus BMASAVP1_1754 in contig CP000525_GR.
KEGG	bmv:BMASAVP1_1754.
PATRIC	19152745. VBIBurMal134057_1648.
TIGR	BMASAVP1_1754.
Phylogenomic databases
HOGENOM	HBG553408.
OMA	HEHEGDA.
ProtClustDB	PRK12549.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1UZE3_BURMS

Accession

Primary (citable) accession number: A1UZE3

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)