A1UUF3 (A1UUF3_BARBK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Peptide chain release factor 3 EMBL ABM45118.1

Gene names

Name:	prfC EMBL ABM45118.1
Ordered Locus Names:	BARBAKC583_1359

Organism

Bartonella bacilliformis (strain ATCC 35685 / KC583) [Complete proteome] [HAMAP]

Taxonomic identifier

360095 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella › Bartonella bacilliformis

Protein attributes

Sequence length	525 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP By similarity.
Subcellular location	Cytoplasm By similarity SAAS SAAS004548.

Ontologies

Keywords
Biological process	Protein biosynthesis SAAS SAAS004548
Cellular component	Cytoplasm SAAS SAAS004548
Ligand	GTP-binding RuleBase RU000323 SAAS SAAS004548 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro translation release factor activity, codon specific Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1UUF3 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 1AC33406B73DC71D	FASTA	525	59,350
	10 20 30 40 50 60 MDCRVQEVKR RRTFAIIAHP DAGKTTLTEK LLLFGGAIQL AGEVKAKKDR IQTRSDWMNI 70 80 90 100 110 120 ERDRGISVVT SVMTFEYEDH IFNLLDTPGH EDFADDTYRT LTAVDSAIMV LDGARGIEPR 130 140 150 160 170 180 TLKLFEVCRM RDIPIVTFVN KMDREACDPL EILDEIEEKL ALDTAPITWP IGMGKDFAGT 190 200 210 220 230 240 FDLHHNSFRQ HDDEITSRAV SGPDEVADLL PEYQRSLFIE GVELARNACK HFDIQAFREG 250 260 270 280 290 300 HMTPVYFGSA LRNFGVRDLI NALVDFGPSP RDQMADQRTV SADEPKMTGF VFKIQANMDP 310 320 330 340 350 360 NHRDRIAFLR VCSGRLERSM KTKLVRTGKP MTLSSPQFFF ARSRQIADQA YAGDVVGIPN 370 380 390 400 410 420 HGTLRIGDTL TEGEDILFKG VPNFAPEILR RVCLHDPMKA KKLKQALQQM AEEGVVQLFT 430 440 450 460 470 480 PDDGSPALVG VIGALQIDVL TERLKVEYSL SVGFEPARFN VCRWISAESK DELQKFLTNH 490 500 510 520 RFAIAYDLDN DPVFLAENAF SLNYEAERAP KIKFATFKDY QTRSE

References

[1]

Hendrix L., Mohamoud Y., Radune D., Shvartsbeyn A., Daugherty S., Dodson R., Durkin A.S., Harkins D., Huot H., Kothari S.P., Madupu R., Li J., Nelson W.C., Shrivastava S., Giglio M.G., Haft D., Selengut J., Fraser-Ligget C., Seshadri R. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35685 / KC583.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000524 Genomic DNA. Translation: ABM45118.1.
RefSeq	YP_989606.1. NC_008783.1.
3D structure databases
ProteinModelPortal	A1UUF3.
ModBase	Search...
Protein-protein interaction databases
STRING	360095.BARBAKC583_1359.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABM45118; ABM45118; BARBAKC583_1359.
GeneID	4684212.
KEGG	bbk:BARBAKC583_1359.
PATRIC	20539039. VBIBarBac6912_1332.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4108.
HOGENOM	HOG000236725.
KO	K02837.
OMA	SDFMEIE.
ProtClustDB	CLSK2298086.
Enzyme and pathway databases
BioCyc	BBAC360095:GHRY-1359-MONOMER.
Family and domain databases
InterPro	IPR000795. EF_GTP-bd_dom. IPR009022. EFG_III-V. IPR004548. PrfC. IPR005225. Small_GTP-bd_dom. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF54980. EFG_III_V. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00503. prfC. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1UUF3_BARBK

Accession

Primary (citable) accession number: A1UUF3

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)