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A1UTQ2

- A1UTQ2_BARBK

UniProt

A1UTQ2 - A1UTQ2_BARBK

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Protein

Alanine racemase

Gene

alr

Organism
Bartonella bacilliformis (strain ATCC 35685 / KC583)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei47 – 471Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei146 – 1461SubstrateUniRule annotation
Active sitei268 – 2681Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei316 – 3161Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBBAC360095:GHRY-1094-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:BARBAKC583_1093Imported
OrganismiBartonella bacilliformis (strain ATCC 35685 / KC583)Imported
Taxonomic identifieri360095 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
ProteomesiUP000000643: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei47 – 471N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi360095.BARBAKC583_1093.

Structurei

3D structure databases

ProteinModelPortaliA1UTQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031445.
KOiK01775.
OMAiFIMSHLA.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

A1UTQ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNQLVDYKTN AELPYTTVAT IDLGAIIANY KILAQHIAPA ECSAVVKANA
60 70 80 90 100
YGMGAEKISS ALYQAGCRTF FVSQIQEALQ LKTILPSNIT LVLLNGFPPT
110 120 130 140 150
TEEFVAQAGL IPVLNSWHAI ESWQMLCQKK HQKFPAIIQI DTHMNRLGLD
160 170 180 190 200
QEELQQLIKQ PTIFEKANIK YIMSHLSNGD DATHASNDTQ LTAMKTALAQ
210 220 230 240 250
LPTCKVSLAN SGGIFLNSDF YFDLVRPGIA LYGVDPHGKC PTPIKPVLKL
260 270 280 290 300
ETQVIQSRHV DAGTPVGYGG SFVTSRPSTL TTISIGYADG WLRTLSNKGV
310 320 330 340 350
VYFNGHKLPI IGRISMDSTI VDATDLECEK PKIGDWVELI GPHQTVEDVA
360 370
ADADTIPYEI LTSLGPRCKR IYI
Length:373
Mass (Da):40,829
Last modified:February 6, 2007 - v1
Checksum:iB472476C7FEFD459
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000524 Genomic DNA. Translation: ABM45232.1.
RefSeqiWP_005767675.1. NC_008783.1.
YP_989355.1. NC_008783.1.

Genome annotation databases

EnsemblBacteriaiABM45232; ABM45232; BARBAKC583_1093.
GeneIDi4684847.
KEGGibbk:BARBAKC583_1093.
PATRICi20538479. VBIBarBac6912_1055.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000524 Genomic DNA. Translation: ABM45232.1 .
RefSeqi WP_005767675.1. NC_008783.1.
YP_989355.1. NC_008783.1.

3D structure databases

ProteinModelPortali A1UTQ2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 360095.BARBAKC583_1093.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM45232 ; ABM45232 ; BARBAKC583_1093 .
GeneIDi 4684847.
KEGGi bbk:BARBAKC583_1093.
PATRICi 20538479. VBIBarBac6912_1055.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031445.
KOi K01775.
OMAi FIMSHLA.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BBAC360095:GHRY-1094-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35685 / KC583Imported.

Entry informationi

Entry nameiA1UTQ2_BARBK
AccessioniPrimary (citable) accession number: A1UTQ2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 26, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3