Reviewed, UniProtKB/Swiss-Prot A1UTE7 (UBIC_BARBK)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	BARBAKC583_0971

Organism

Bartonella bacilliformis (strain ATCC 35685 / KC583) [Complete proteome] [HAMAP]

Taxonomic identifier

360095 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	171 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 171	171	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000292063
Sites
	Binding site	36	1	Substrate; via amide nitrogen By similarity
	Binding site	78	1	Substrate By similarity
	Binding site	116	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1UTE7-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 7B1A000350C0F208	FASTA	171	19,982
	10 20 30 40 50 60 MFRTEDSILP PLEWLSDNNS SVPPAIYDWL MELGSMTLRF ERYCTRVHVE PRHEYFIARN 70 80 90 100 110 120 ELKEEAEHLP ESSLYWLREV VLMGDNQPWL LGRTVIPQET LAHHSNALMN LGTLPLGRYL 130 140 150 160 170 FSNGELTRDY IHIGRKDSLW ARRSRLRLSG KPLLLTELFL ADSPLYTEDP S

References

[1]

Hendrix L., Mohamoud Y., Radune D., Shvartsbeyn A., Daugherty S., Dodson R., Durkin A.S., Harkins D., Huot H., Kothari S.P., Madupu R., Li J., Nelson W.C., Shrivastava S., Giglio M.G., Haft D., Selengut J., Fraser-Ligget C., Seshadri R. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000524 Genomic DNA. Translation: ABM44670.1.
RefSeq	YP_989250.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1UTE7.
Genome annotation databases
GeneID	4684707.
GenomeReviews	Gene locus BARBAKC583_0971 in contig CP000524_GR.
KEGG	bbk:BARBAKC583_0971.
NMPDR	fig|360095.3.peg.572.
TIGR	BARBAKC583_0971.
Phylogenomic databases
OMA	WGRRSRF.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_BARBK

Accession

Primary (citable) accession number: A1UTE7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)