Reviewed, UniProtKB/Swiss-Prot A1USU3 (SYR_BARBK)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BARBAKC583_0749

Organism

Bartonella bacilliformis (strain ATCC 35685 / KC583) [Complete proteome] [HAMAP]

Taxonomic identifier

360095 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	585 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 585	585	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_1000017989
Regions
	Motif	131 – 141	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	A1USU3-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 77937A5E538DC51B	FASTA	585	66,254
	10 20 30 40 50 60 MNVFKNFEQK IKKSLKESDI KGKNGENLDL SKITVDPPRD SLHGDLSTNA SMVLAKSVGL 70 80 90 100 110 120 NPRTLAEKII ALLKDDPSID HLEVAGSGFI NIKLTKSFWH DVLKLMITSG TDYGRTQIGQ 130 140 150 160 170 180 GKQVNVEYVS ANPTGPMHVG HCRGAVVGDV LANLLQFAGY NVTKEYYIND AGKQIEILAA 190 200 210 220 230 240 SVLLRYREAL GETINKIPEG LYPGEYLIPL GQSLVQEFGD KLLTMDNEKA LSIVKERSID 250 260 270 280 290 300 AMMTMIRQDL ATLNIHHDVF FSERMLYMNN AQAIRNTIND LTLNGYVYKG KLSPPKGQTL 310 320 330 340 350 360 EDWEPHEQTL FRSTDVGDDQ DRVLIKSDGS YTYFAADVAY FRDKFHRHFD EMIYVLGADH 370 380 390 400 410 420 AGYVKRLEAV AKAISGNKAK LTAFLCQLVK LFRNGHPVRM SKREGSFITL RDVVKEVGRD 430 440 450 460 470 480 PVRFMMLYRK CEAPLDFDLE KVTEQSKDNP IFYVQYAHAR CHSVFRQAQE NLQIENPSND 490 500 510 520 530 540 LMIAHLDQLT NDSEISLIHK LAQYPRIIEQ AIVYKEPHRL AFYLYDLASN FHGHWNKGND 550 560 570 580 NPELRFIKPN NKKLSLARLG LVQAFINVLS SGLKIVEVKA PTEMR

References

[1]

Hendrix L., Mohamoud Y., Radune D., Shvartsbeyn A., Daugherty S., Dodson R., Durkin A.S., Harkins D., Huot H., Kothari S.P., Madupu R., Li J., Nelson W.C., Shrivastava S., Giglio M.G., Haft D., Selengut J., Fraser-Ligget C., Seshadri R. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000524 Genomic DNA. Translation: ABM44962.1.
RefSeq	YP_989046.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1USU3.
Genome annotation databases
GeneID	4684762.
GenomeReviews	Gene locus BARBAKC583_0749 in contig CP000524_GR.
KEGG	bbk:BARBAKC583_0749.
NMPDR	fig|360095.3.peg.770.
TIGR	BARBAKC583_0749.
Phylogenomic databases
OMA	ADHHGYV.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BARBK

Accession

Primary (citable) accession number: A1USU3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)