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Protein

Elongation factor Tu 2

Gene

tuf2

more
Organism
Bartonella bacilliformis (strain ATCC 35685 / KC583)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi76 – 80GTPUniRule annotation5
Nucleotide bindingi131 – 134GTPUniRule annotation4

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Tu 2UniRule annotation
Short name:
EF-Tu 2UniRule annotation
Gene namesi
Name:tuf2UniRule annotation
Ordered Locus Names:BARBAKC583_0664
AND
Name:tuf3UniRule annotation
Ordered Locus Names:BARBAKC583_0696
OrganismiBartonella bacilliformis (strain ATCC 35685 / KC583)
Taxonomic identifieri360095 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
Proteomesi
  • UP000000643 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003373211 – 391Elongation factor Tu 2Add BLAST391

Proteomic databases

PRIDEiA1USL2.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi360095.BARBAKC583_0696.

Structurei

3D structure databases

ProteinModelPortaliA1USL2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 201tr-type GAdd BLAST192

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni55 – 59G2By similarity5
Regioni76 – 79G3By similarity4
Regioni131 – 134G4By similarity4
Regioni169 – 171G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
HOGENOMiHOG000229290.
KOiK02358.
OMAiYSTATRH.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1USL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKYFGEFK AYDQIDAAPE
60 70 80 90 100
ERARGITIST AHVEYETDQR HYAHVDCPGH ADYVKNMITG AAQMDGAILV
110 120 130 140 150
VSAADGPMPQ TREHILLARQ VGVPAIVVFL NKVDQVDDAE LLELVELEVR
160 170 180 190 200
ELLSKYDFPG DDIPIVKGSA LAALEDSDKS IGEDAVRLLM SEVDRYIPTP
210 220 230 240 250
ERPVDQSFLM PIEDVFSISG RGTVVTGRVE RGVVKVGEEI EIVGIRPTSK
260 270 280 290 300
TTVTGVEMFR KLLDQGQAGD NIGALLRGID REGIERGQVL AKPGSVTPHT
310 320 330 340 350
KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGIVT LPEGTEMVMP
360 370 380 390
GDNVAMDVSL IVPIAMEEKL RFAIREGGRT VGAGIVSKII E
Length:391
Mass (Da):42,787
Last modified:February 6, 2007 - v1
Checksum:i8966A15ED50DE845
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000524 Genomic DNA. Translation: ABM44569.1.
CP000524 Genomic DNA. Translation: ABM45676.1.
RefSeqiWP_005766892.1. NC_008783.1.

Genome annotation databases

EnsemblBacteriaiABM44569; ABM44569; BARBAKC583_0664.
ABM45676; ABM45676; BARBAKC583_0696.
GeneIDi4684260.
KEGGibbk:BARBAKC583_0664.
bbk:BARBAKC583_0696.
PATRICi20537615. VBIBarBac6912_0645.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000524 Genomic DNA. Translation: ABM44569.1.
CP000524 Genomic DNA. Translation: ABM45676.1.
RefSeqiWP_005766892.1. NC_008783.1.

3D structure databases

ProteinModelPortaliA1USL2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi360095.BARBAKC583_0696.

Proteomic databases

PRIDEiA1USL2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM44569; ABM44569; BARBAKC583_0664.
ABM45676; ABM45676; BARBAKC583_0696.
GeneIDi4684260.
KEGGibbk:BARBAKC583_0664.
bbk:BARBAKC583_0696.
PATRICi20537615. VBIBarBac6912_0645.

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
HOGENOMiHOG000229290.
KOiK02358.
OMAiYSTATRH.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiIPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEFTU2_BARBK
AccessioniPrimary (citable) accession number: A1USL2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.