Reviewed, UniProtKB/Swiss-Prot A1US45 (PSD_BARBK)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	BARBAKC583_0483

Organism

Bartonella bacilliformis (strain ATCC 35685 / KC583) [Complete proteome] [HAMAP]

Taxonomic identifier

360095 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity.
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000026624
	Chain	190 – 232	43	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000026625
Sites
	Site	189 – 190	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	190	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1US45-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 74CE6CC025B89F79	FASTA	232	25,879
	10 20 30 40 50 60 MSVFRSIRDG VVPIHKEGYP FIVAFFVASL ILGWIWDPLF WFGLVLTVWC IYFFRDPERV 70 80 90 100 110 120 TPMNADWVVS PADGRISFVG LCVPPEELDL GKNEMMRVSV FMDVFSCHIN RAPVSGTIES 130 140 150 160 170 180 IVYSPGKFVN ADLDKASEFN ERNGVVIDSK HGKIGVVQIA GLVARRIICW SKEDDSVAAG 190 200 210 220 230 QRFGMIRFGS RLDVYMPAEI KLRVAVGQTS IAGETVLGSF DSDITTTDFR LN

References

[1]

Hendrix L., Mohamoud Y., Radune D., Shvartsbeyn A., Daugherty S., Dodson R., Durkin A.S., Harkins D., Huot H., Kothari S.P., Madupu R., Li J., Nelson W.C., Shrivastava S., Giglio M.G., Haft D., Selengut J., Fraser-Ligget C., Seshadri R. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000524 Genomic DNA. Translation: ABM45376.1.
RefSeq	YP_988798.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1US45.
Genome annotation databases
GeneID	4684110.
GenomeReviews	Gene locus BARBAKC583_0483 in contig CP000524_GR.
KEGG	bbk:BARBAKC583_0483.
NMPDR	fig|360095.3.peg.177.
TIGR	BARBAKC583_0483.
Phylogenomic databases
OMA	DKASEDN.
Family and domain databases
HAMAP	MF_00664. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase_related. [Graphical view]
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_BARBK

Accession

Primary (citable) accession number: A1US45

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)