Reviewed, UniProtKB/Swiss-Prot A1URW3 (AROC_BARBK)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	BARBAKC583_0397

Organism

Bartonella bacilliformis (strain ATCC 35685 / KC583) [Complete proteome] [HAMAP]

Taxonomic identifier

360095 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 364	364	Chorismate synthase HAMAP MF_00300		PRO_1000022461

Sequences

	Sequence		Length	Mass (Da)
	A1URW3-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 541602EBF8420D1F	FASTA	364	38,996
	10 20 30 40 50 60 MSHNTFGHLF RVTTWGESHG AALGCVIDGC PPGIAFTLTE IQAYLNKRRP GHSEYTTQRR 70 80 90 100 110 120 ELDQVEILSG VVSQNDGKAL VTTGTPISMF IRNVDHHSED YNAIMHKYRP GHADYTYDVK 130 140 150 160 170 180 YGIRDHRGGG RASARETVVR VAAGALARKI VPGLIVRGAV TAIGPHNIDR DRWDWSEVDK 190 200 210 220 230 240 NPFFSPDAQA ACVFANYISQ LCKTGSSVGA IVEIVAENVP AGLGAPVYAK LDQDIASFLM 250 260 270 280 290 300 SINAVKGIEI GDGFAAAHLT GEENADEMRM GSDGKPVFLS NHAGGILGGI SNGQPIVARF 310 320 330 340 350 360 AVKPTSSILT PSRSIDIEGN DVNVMTKGRH DPCVGIRAVP VGEAMVACAI ADHYLRHRGQ VGCI

References

[1]

Hendrix L., Mohamoud Y., Radune D., Shvartsbeyn A., Daugherty S., Dodson R., Durkin A.S., Harkins D., Huot H., Kothari S.P., Madupu R., Li J., Nelson W.C., Shrivastava S., Giglio M.G., Haft D., Selengut J., Fraser-Ligget C., Seshadri R. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000524 Genomic DNA. Translation: ABM44553.1.
RefSeq	YP_988716.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1URW3.
Genome annotation databases
GeneID	4684119.
GenomeReviews	Gene locus BARBAKC583_0397 in contig CP000524_GR.
KEGG	bbk:BARBAKC583_0397.
NMPDR	fig|360095.3.peg.445.
TIGR	BARBAKC583_0397.
Phylogenomic databases
OMA	SRFTTQR.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
ProDom	PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_BARBK

Accession

Primary (citable) accession number: A1URW3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)