Skip Header

Contribute Send feedback
Read comments (?) or add your own

A1URW3 (AROC_BARBK) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:BARBAKC583_0397
OrganismBartonella bacilliformis (strain ATCC 35685 / KC583) [Complete proteome] [HAMAP]
Taxonomic identifier360095 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 364364Chorismate synthase HAMAP MF_00300
PRO_1000022461

Sequences

Sequence LengthMass (Da)Tools
A1URW3 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 541602EBF8420D1F

FASTA36438,996
        10         20         30         40         50         60 
MSHNTFGHLF RVTTWGESHG AALGCVIDGC PPGIAFTLTE IQAYLNKRRP GHSEYTTQRR 

        70         80         90        100        110        120 
ELDQVEILSG VVSQNDGKAL VTTGTPISMF IRNVDHHSED YNAIMHKYRP GHADYTYDVK 

       130        140        150        160        170        180 
YGIRDHRGGG RASARETVVR VAAGALARKI VPGLIVRGAV TAIGPHNIDR DRWDWSEVDK 

       190        200        210        220        230        240 
NPFFSPDAQA ACVFANYISQ LCKTGSSVGA IVEIVAENVP AGLGAPVYAK LDQDIASFLM 

       250        260        270        280        290        300 
SINAVKGIEI GDGFAAAHLT GEENADEMRM GSDGKPVFLS NHAGGILGGI SNGQPIVARF 

       310        320        330        340        350        360 
AVKPTSSILT PSRSIDIEGN DVNVMTKGRH DPCVGIRAVP VGEAMVACAI ADHYLRHRGQ 


VGCI

« Hide

References

[1]Hendrix L., Mohamoud Y., Radune D., Shvartsbeyn A., Daugherty S., Dodson R., Durkin A.S., Harkins D., Huot H., Kothari S.P., Madupu R., Li J., Nelson W.C., Shrivastava S., Giglio M.G., Haft D., Selengut J., Fraser-Ligget C., Seshadri R.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35685 / KC583.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000524 Genomic DNA. Translation: ABM44553.1.
RefSeqYP_988716.1. NC_008783.1.

3D structure databases

ProteinModelPortalA1URW3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1URW3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4684119.
GenomeReviewsGene locus BARBAKC583_0397 in contig CP000524_GR.
KEGGbbk:BARBAKC583_0397.
NMPDRfig|360095.3.peg.445.
PATRIC20537061. VBIBarBac6912_0380.
TIGRBARBAKC583_0397.

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMASRFTTQR.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycBBAC360095:BARBAKC583_0397-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_BARBK
AccessionPrimary (citable) accession number: A1URW3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents