Reviewed, UniProtKB/Swiss-Prot A1URA6 (GLMM_BARBK)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BARBAKC583_0171

Organism

Bartonella bacilliformis (strain ATCC 35685 / KC583) [Complete proteome] [HAMAP]

Taxonomic identifier

360095 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	450 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 450	450	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000301280
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
	Metal binding	248	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1URA6-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 22A2CBCC7764DA31	FASTA	450	49,421
	10 20 30 40 50 60 MARKYFGTDG IRGKANIFPM TPDFAMKVGI AVGVLFRSKA TSRRVVIGKD TRLSCYMLEN 70 80 90 100 110 120 ALVAGFTAAG MDAFLLGPIP TPAVAMLCRS LRADIGVMIS ASHNAFYDNG IKLFGPDGFK 130 140 150 160 170 180 LSDEKETKIE ALLDSDISEL PLANCEEIGR AKRVEGDIYR YIEYAKRTLP RDVRLDALRI 190 200 210 220 230 240 VVDCANGATY KAAPRALWEL GAEVIAINDE PNGFNINQEC GSTDLTSLRN KVHEVRADVG 250 260 270 280 290 300 IALDGDGDRV LMVDEKGQMI DGDQLIAVIA EHWHKTGRLH HKGIVTTVMS NLGLERFLSE 310 320 330 340 350 360 KGLKLIRTDV GDRYVVDMMR QKKYNIGGES SGHIILSDFC TTGDGLVAAL QVLACMKESQ 370 380 390 400 410 420 QPMSQLCKRF EPVPQILKNK VVHNKNVLQK SEVQAALTKA SEHLGKEGRL LVRASGTEPV 430 440 450 IRVMAEGDDR KAMTAIVDDL ITLIARHDHD

References

[1]

Hendrix L., Mohamoud Y., Radune D., Shvartsbeyn A., Daugherty S., Dodson R., Durkin A.S., Harkins D., Huot H., Kothari S.P., Madupu R., Li J., Nelson W.C., Shrivastava S., Giglio M.G., Haft D., Selengut J., Fraser-Ligget C., Seshadri R. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000524 Genomic DNA. Translation: ABM45449.1.
RefSeq	YP_988509.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1URA6.
Genome annotation databases
GeneID	4683927.
GenomeReviews	Gene locus BARBAKC583_0171 in contig CP000524_GR.
KEGG	bbk:BARBAKC583_0171.
NMPDR	fig|360095.3.peg.1127.
TIGR	BARBAKC583_0171.
Phylogenomic databases
OMA	VHDRYIE.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BARBK

Accession

Primary (citable) accession number: A1URA6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)