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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Bartonella bacilliformis (strain ATCC 35685 / KC583)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei118SubstrateUniRule annotation1
Binding sitei151SubstrateUniRule annotation1
Binding sitei201ATPUniRule annotation1
Binding sitei323ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi353 – 356ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBBAC360095:G1G7W-135-MONOMER
UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:BARBAKC583_0140
OrganismiBartonella bacilliformis (strain ATCC 35685 / KC583)
Taxonomic identifieri360095 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
Proteomesi
  • UP000000643 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000579691 – 400Phosphoglycerate kinaseAdd BLAST400

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi360095.BARBAKC583_0140

Structurei

3D structure databases

ProteinModelPortaliA1UR75
SMRiA1UR75
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZA Bacteria
COG0126 LUCA
HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

Gene3Di3.40.50.12603 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

A1UR75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFRTINEAN VSGKRVLVRV DFNVPMSQGK VCDNTRLERH KETICALQKR
60 70 80 90 100
GAKIILLSHC SRPRGKIVPE LSLRPVAKAL ETIMGQQIFF VEECIGAPVQ
110 120 130 140 150
TAVEALQEGQ ILLLENLRFY KEEEDNNADF AEALAQQGDL YVNDAFSVSH
160 170 180 190 200
RAHASVEAIT HYLPSYAGMA LQRELQALEK GLDNPKKPVT AIVGGAKVSS
210 220 230 240 250
KLFVLNHLVT KVDYLVIGGG MANNFLMAQG HNVGKSLCEP MLMDMVKDVI
260 270 280 290 300
EKARESHCTL VLPVDAVVGL QCETGTPHHH CMIEAIPDEG MILDIGEHSI
310 320 330 340 350
ARINTVIDAS ATLVWNGPLG VFEVSPFDHG TIAVARYAAA RSQKGHCVSI
360 370 380 390 400
AGGGDTVFAL NHAGVADDFT YLSTAGGAFL EWMEGKTLPG VLALMQDLKN
Length:400
Mass (Da):43,421
Last modified:February 6, 2007 - v1
Checksum:iEA63F29C60216A6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000524 Genomic DNA Translation: ABM45059.1
RefSeqiWP_005765917.1, NC_008783.1

Genome annotation databases

EnsemblBacteriaiABM45059; ABM45059; BARBAKC583_0140
GeneIDi4684315
KEGGibbk:BARBAKC583_0140
PATRICifig|360095.6.peg.140

Similar proteinsi

Entry informationi

Entry nameiPGK_BARBK
AccessioniPrimary (citable) accession number: A1UR75
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: February 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome