A1UN51 (PATR_MYCSK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Ordered Locus Names:	Mkms_5070

Organism

Mycobacterium sp. (strain KMS) [Complete proteome] [HAMAP]

Taxonomic identifier

189918 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	358 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 358	358	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_1000024498
Amino acid modifications
	Modified residue	222	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1UN51 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 2B0699A5838F4325	FASTA	358	38,892
	10 20 30 40 50 60 MTARLRPELA DIPAYTPGKT VPGAIKIASN ETVHGPLPSV RAAIEKATDQ LNRYPDNGYL 70 80 90 100 110 120 ELREHLASHL DKNLGAGAFT PEQIAVGCGS VSLCQQLIQI TSSVGDEVIF AWRSFEIYPL 130 140 150 160 170 180 QVRTAGATPV QVPLRDHTHD LDAMLAAITD RTRLIFVCNP NNPTSTVVDP AALKRFVEAV 190 200 210 220 230 240 PPHILVVIDE AYVEYIRGDQ VPDSFGLVRA HPNVVVLRTF SKAYGLAGLR IGYAVADADI 250 260 270 280 290 300 VTALGKVYVP FSATSISQAA AIASIDAADE LLARTDQVVA ERDRVTAALR EAGFTLPPSQ 310 320 330 340 350 SNFVWLPLAE RTLDFVRRAA ENRLVVRPYG EDGVRVTIAA PHENDAFLEF ARNWIGQP

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. KMS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KMS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000518 Genomic DNA. Translation: ABL94259.1.
RefSeq	YP_941049.1. NC_008705.1.
3D structure databases
ProteinModelPortal	A1UN51.
ModBase	Search...
Protein-protein interaction databases
STRING	A1UN51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000053281; EBMYCP00000051505; EBMYCG00000053276.
GeneID	4612752.
GenomeReviews	Gene locus Mkms_5070 in contig CP000518_GR.
KEGG	mkm:Mkms_5070.
PATRIC	18109194. VBIMycSp70743_5599.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0079.
GeneTree	EBGT00070000031717.
HOGENOM	HBG646350.
OMA	NNTKIVW.
ProtClustDB	PRK03321.
Enzyme and pathway databases
BioCyc	MSP189918:MKMS_5070-MONOMER.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_MYCSK

Accession

Primary (citable) accession number: A1UN51

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program