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A1ULY7

- A1ULY7_MYCSK

UniProt

A1ULY7 - A1ULY7_MYCSK

Protein

Adenylosuccinate lyase

Gene

Mkms_4654

Organism
Mycobacterium sp. (strain KMS)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotation
    N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
    2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

    GO - Biological processi

    1. purine ribonucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Biological processi

    Purine biosynthesisUniRule annotation

    Enzyme and pathway databases

    BioCyciMSP189918:GH4X-4701-MONOMER.
    UniPathwayiUPA00074; UER00132.
    UPA00075; UER00336.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Adenylosuccinate lyaseUniRule annotation (EC:4.3.2.2UniRule annotation)
    Short name:
    ASLUniRule annotation
    Alternative name(s):
    AdenylosuccinaseUniRule annotation
    Gene namesi
    Ordered Locus Names:Mkms_4654Imported
    OrganismiMycobacterium sp. (strain KMS)Imported
    Taxonomic identifieri189918 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000638: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi189918.Mkms_4654.

    Structurei

    3D structure databases

    ProteinModelPortaliA1ULY7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0015.
    HOGENOMiHOG000033913.
    KOiK01756.
    OMAiKGPMGTS.
    OrthoDBiEOG686NDB.

    Family and domain databases

    Gene3Di1.10.275.10. 1 hit.
    InterProiIPR019468. AdenyloSucc_lyase_C.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    IPR004769. Pur_lyase.
    [Graphical view]
    PANTHERiPTHR11444. PTHR11444. 1 hit.
    PfamiPF10397. ADSL_C. 1 hit.
    PF00206. Lyase_1. 1 hit.
    [Graphical view]
    PRINTSiPR00149. FUMRATELYASE.
    SMARTiSM00998. ADSL_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48557. SSF48557. 1 hit.
    TIGRFAMsiTIGR00928. purB. 1 hit.
    PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1ULY7-1 [UniParc]FASTAAdd to Basket

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    MTIPNVLANR YASEDMVAIW SPEAKIVAER RLWLAVLRAQ IELGMGNTVV    50
    PDGVVADYER VLDQVDLASI AARERVTRHD VKARIEEFNA LAGHEHVHKG 100
    MTSRDLTENV EQLQIRRSLE LVHAHGVAVV ARLAEKAVSY RDLVMAGRSH 150
    NVAAQATTLG KRFASAAEET LLALQRVEEL IARYPLRGIK GPMGTAQDML 200
    DLFGGDTAKL ADLERRVAEF LGFRDVFTSV GQVYPRSLDH DVVSALVQLG 250
    AGPSSLAHTI RLMAGHELVT EGFAPGQVGS SAMPHKMNTR SCERVNGLQV 300
    VLRGYGSMAA ELAGAQWNEG DVFCSVVRRV ALPDAFFAID GQTETFLTVL 350
    DEFGAYPAVI QRELDRYLPF LATTRILIAA VRAGVGRETA HEVIKEHAVA 400
    VALAMREKGQ EPDLLDRLAA DPRLPLDRVA LEDALADKQA FSGAAGDQVD 450
    RVAQAVDELV SRYPEAAKYT SGAIL 475
    Length:475
    Mass (Da):51,696
    Last modified:February 6, 2007 - v1
    Checksum:i082A0E551D7FE86B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000518 Genomic DNA. Translation: ABL93845.1.
    RefSeqiWP_011768377.1. NC_008705.1.
    YP_940635.1. NC_008705.1.

    Genome annotation databases

    EnsemblBacteriaiABL93845; ABL93845; Mkms_4654.
    GeneIDi4612602.
    KEGGimkm:Mkms_4654.
    PATRICi18108358. VBIMycSp70743_5188.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000518 Genomic DNA. Translation: ABL93845.1 .
    RefSeqi WP_011768377.1. NC_008705.1.
    YP_940635.1. NC_008705.1.

    3D structure databases

    ProteinModelPortali A1ULY7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 189918.Mkms_4654.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABL93845 ; ABL93845 ; Mkms_4654 .
    GeneIDi 4612602.
    KEGGi mkm:Mkms_4654.
    PATRICi 18108358. VBIMycSp70743_5188.

    Phylogenomic databases

    eggNOGi COG0015.
    HOGENOMi HOG000033913.
    KOi K01756.
    OMAi KGPMGTS.
    OrthoDBi EOG686NDB.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00132 .
    UPA00075 ; UER00336 .
    BioCyci MSP189918:GH4X-4701-MONOMER.

    Family and domain databases

    Gene3Di 1.10.275.10. 1 hit.
    InterProi IPR019468. AdenyloSucc_lyase_C.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    IPR004769. Pur_lyase.
    [Graphical view ]
    PANTHERi PTHR11444. PTHR11444. 1 hit.
    Pfami PF10397. ADSL_C. 1 hit.
    PF00206. Lyase_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00149. FUMRATELYASE.
    SMARTi SM00998. ADSL_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48557. SSF48557. 1 hit.
    TIGRFAMsi TIGR00928. purB. 1 hit.
    PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KMSImported.

    Entry informationi

    Entry nameiA1ULY7_MYCSK
    AccessioniPrimary (citable) accession number: A1ULY7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 6, 2007
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3