Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1ULY7

- A1ULY7_MYCSK

UniProt

A1ULY7 - A1ULY7_MYCSK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Adenylosuccinate lyase

Gene

Mkms_4654

Organism
Mycobacterium sp. (strain KMS)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotation
N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
  2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' AMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Biological processi

Purine biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciMSP189918:GH4X-4701-MONOMER.
UniPathwayiUPA00074; UER00132.
UPA00075; UER00336.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylosuccinate lyaseUniRule annotation (EC:4.3.2.2UniRule annotation)
Short name:
ASLUniRule annotation
Alternative name(s):
AdenylosuccinaseUniRule annotation
Gene namesi
Ordered Locus Names:Mkms_4654Imported
OrganismiMycobacterium sp. (strain KMS)Imported
Taxonomic identifieri189918 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000638: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi189918.Mkms_4654.

Structurei

3D structure databases

ProteinModelPortaliA1ULY7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0015.
HOGENOMiHOG000033913.
KOiK01756.
OMAiKGPMGTS.
OrthoDBiEOG686NDB.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SMARTiSM00998. ADSL_C. 1 hit.
[Graphical view]
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00928. purB. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1ULY7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTIPNVLANR YASEDMVAIW SPEAKIVAER RLWLAVLRAQ IELGMGNTVV
60 70 80 90 100
PDGVVADYER VLDQVDLASI AARERVTRHD VKARIEEFNA LAGHEHVHKG
110 120 130 140 150
MTSRDLTENV EQLQIRRSLE LVHAHGVAVV ARLAEKAVSY RDLVMAGRSH
160 170 180 190 200
NVAAQATTLG KRFASAAEET LLALQRVEEL IARYPLRGIK GPMGTAQDML
210 220 230 240 250
DLFGGDTAKL ADLERRVAEF LGFRDVFTSV GQVYPRSLDH DVVSALVQLG
260 270 280 290 300
AGPSSLAHTI RLMAGHELVT EGFAPGQVGS SAMPHKMNTR SCERVNGLQV
310 320 330 340 350
VLRGYGSMAA ELAGAQWNEG DVFCSVVRRV ALPDAFFAID GQTETFLTVL
360 370 380 390 400
DEFGAYPAVI QRELDRYLPF LATTRILIAA VRAGVGRETA HEVIKEHAVA
410 420 430 440 450
VALAMREKGQ EPDLLDRLAA DPRLPLDRVA LEDALADKQA FSGAAGDQVD
460 470
RVAQAVDELV SRYPEAAKYT SGAIL
Length:475
Mass (Da):51,696
Last modified:February 6, 2007 - v1
Checksum:i082A0E551D7FE86B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000518 Genomic DNA. Translation: ABL93845.1.
RefSeqiWP_011768377.1. NC_008705.1.
YP_940635.1. NC_008705.1.

Genome annotation databases

EnsemblBacteriaiABL93845; ABL93845; Mkms_4654.
GeneIDi4612602.
KEGGimkm:Mkms_4654.
PATRICi18108358. VBIMycSp70743_5188.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000518 Genomic DNA. Translation: ABL93845.1 .
RefSeqi WP_011768377.1. NC_008705.1.
YP_940635.1. NC_008705.1.

3D structure databases

ProteinModelPortali A1ULY7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 189918.Mkms_4654.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL93845 ; ABL93845 ; Mkms_4654 .
GeneIDi 4612602.
KEGGi mkm:Mkms_4654.
PATRICi 18108358. VBIMycSp70743_5188.

Phylogenomic databases

eggNOGi COG0015.
HOGENOMi HOG000033913.
KOi K01756.
OMAi KGPMGTS.
OrthoDBi EOG686NDB.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00132 .
UPA00075 ; UER00336 .
BioCyci MSP189918:GH4X-4701-MONOMER.

Family and domain databases

Gene3Di 1.10.275.10. 1 hit.
InterProi IPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view ]
PANTHERi PTHR11444. PTHR11444. 1 hit.
Pfami PF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view ]
PRINTSi PR00149. FUMRATELYASE.
SMARTi SM00998. ADSL_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48557. SSF48557. 1 hit.
TIGRFAMsi TIGR00928. purB. 1 hit.
PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KMSImported.

Entry informationi

Entry nameiA1ULY7_MYCSK
AccessioniPrimary (citable) accession number: A1ULY7
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3