A1UG95 (A1UG95_MYCSK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrodipicolinate synthase EMBL ABL91853.1

Gene names

Ordered Locus Names:

Mkms_2658

Organism

Mycobacterium sp. (strain KMS) [Complete proteome] [HAMAP]

Taxonomic identifier

189918 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263
Subunit structure	Homotetramer By similarity. SAAS SAAS005263
Subcellular location	Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Diaminopimelate biosynthesis SAAS SAAS005263 Lysine biosynthesis SAAS SAAS005263
Cellular component	Cytoplasm SAAS SAAS005263
Ligand	Schiff base SAAS SAAS005263
Molecular function	Lyase SAAS SAAS005263
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	diaminopimelate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	dihydrodipicolinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1UG95 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: DC237DC62766A2AA	FASTA	316	33,958
	10 20 30 40 50 60 MTARRDPHSI RGSITPLMTP FTDDGAVDHR SLANLVNWQL ASGSHGISIG GSTGEPGAQS 70 80 90 100 110 120 VAERLAAIAT VMKSVSGRAP VVAGTGTAQL DETIELTGRA AELGIDAALV ITPYYARPTQ 130 140 150 160 170 180 EALYRWYKTV AEEYPDLPIL AYNVPVRTAV DLAPETIARL YRDVENFVGV KETTKDFEHF 190 200 210 220 230 240 SRVMHLCGPD IIVWSGIELL CLPLLALGGT GFLSATANIA PAAHARMYEL WIAGAHEEAR 250 260 270 280 290 300 AIHYGLHPLV DLLFVETNPA PGKWLLKDLG LIASDHVRPP LITPTPGALE RIAVLRRAGE 310 KFLTPVGDFA LEGAFA

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. KMS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KMS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000518 Genomic DNA. Translation: ABL91853.1.
RefSeq	YP_938643.1. NC_008705.1.
3D structure databases
ProteinModelPortal	A1UG95.
ModBase	Search...
Protein-protein interaction databases
STRING	A1UG95.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000054101; EBMYCP00000052325; EBMYCG00000054096.
GeneID	4615944.
GenomeReviews	Gene locus Mkms_2658 in contig CP000518_GR.
KEGG	mkm:Mkms_2658.
PATRIC	18104280. VBIMycSp70743_3177.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0329.
GeneTree	EBGT00050000016215.
HOGENOM	HBG358848.
OMA	GSTNHAE.
ProtClustDB	CLSK955639.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002220. Dihydrodipicolinate_synth-like. IPR020625. Dihydrodipicolinate_synth_AS. IPR005263. Dihydrodipicolinate_synth_DapA. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01714.
PANTHER	PTHR12128. DHDPS. 1 hit.
Pfam	PF00701. DHDPS. 1 hit. [Graphical view]
PIRSF	PIRSF001365. DHDPS. 1 hit.
PRINTS	PR00146. DHPICSNTHASE.
TIGRFAMs	TIGR00674. DapA. 1 hit.
PROSITE	PS00666. DHDPS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1UG95_MYCSK

Accession

Primary (citable) accession number: A1UG95

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)