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A1UEU0 (A1UEU0_MYCSK) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Ordered Locus Names:Mkms_2150
OrganismMycobacterium sp. (strain KMS) [Complete proteome] [HAMAP]
Taxonomic identifier189918 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183 EMBL ABL91348.1
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A1UEU0 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: CD96EBDEACE34274

FASTA37138,626
        10         20         30         40         50         60 
MRVGIPTEIK NNEYRVAITP AGVAELTSRG HDVLIQSGAG EGSAISDADF KAAGAQLIAG 

        70         80         90        100        110        120 
ADEVWAEADL LLKVKEPIEP EYSRMREGQT LFTYLHLAAS QPCTDALLAS RTTSIAYETV 

       130        140        150        160        170        180 
QTADGALPLL APMSEVAGRL SAQVGAYHLM RTQGGRGVLM GGVPGVAPAK VVVIGGGMAG 

       190        200        210        220        230        240 
DNAAAVAWGM GAHVTVFDVN INILRKIDAE YGGAIETRYS SRLELEEAVT QADLVIGAVL 

       250        260        270        280        290        300 
IPGAKAPKLV TNSTVAQMKS GAVLVDIAID QGGCFEDSRP TTHDDPTFKV HDAVFYCVAN 

       310        320        330        340        350        360 
MPGAVPRTST FALTNATMPY VLKLADKGWR AACQADPALA KGLSTHAGAL LSEQVAADLD 

       370 
LPFTDPATVL A

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References

[1]"Complete sequence of chromosome of Mycobacterium sp. KMS."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: KMS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000518 Genomic DNA. Translation: ABL91348.1.
RefSeqYP_938138.1. NC_008705.1.

3D structure databases

ProteinModelPortalA1UEU0.
SMRA1UEU0. Positions 1-371.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1UEU0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000054406; EBMYCP00000052630; EBMYCG00000054401.
GeneID4613509.
GenomeReviewsGene locus Mkms_2150 in contig CP000518_GR.
KEGGmkm:Mkms_2150.
PATRIC18103223. VBIMycSp70743_2653.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0686.
GeneTreeEBGT00050000016024.
HOGENOMHBG289735.
OMAVAHGHEV.
ProtClustDBCLSK792072.

Family and domain databases

InterProIPR008142. Ala_DH/PNT_CS1.
IPR008143. Ala_DH/PNT_CS2.
IPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
PROSITEPS00836. ALADH_PNT_1. 1 hit.
PS00837. ALADH_PNT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1UEU0_MYCSK
AccessionPrimary (citable) accession number: A1UEU0
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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