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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Mycobacterium sp. (strain KMS)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei44NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Mkms_2141
OrganismiMycobacterium sp. (strain KMS)
Taxonomic identifieri189918 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000638 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001498271 – 297tRNA pseudouridine synthase BAdd BLAST297

Structurei

3D structure databases

ProteinModelPortaliA1UET1
SMRiA1UET1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT
OrthoDBiPOG091H02G9

Family and domain databases

Gene3Di2.30.130.10, 1 hit
HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR015947 PUA-like_sf
IPR036974 PUA_sf
IPR015225 tRNA_psdUridine_synth_fam2_C
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF09142 TruB_C, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
SSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

A1UET1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGAGVGGGI VIVDKPAGMT SHDVVGRCRR IFGTRKVGHA GTLDPMATGV
60 70 80 90 100
LVVGIDRATK LLGLLTATDK SYEATIRLGQ TTTTEDAEGD VVETTPATGI
110 120 130 140 150
TDEQIGHAVA ALRGEIDQVP SAVSAIKVGG QRAYKLAREG QTVELAARRV
160 170 180 190 200
RIDRFEVLAI RRVDGFVDVD VAVDCSSGTY IRALARDVGV TLGVGGHLTL
210 220 230 240 250
LRRTRVGRFG LDEAYPLDAL ADEPRLSHSL DEACLLSFPR RDLTPAEAES
260 270 280 290
TRHGRALAPA GIDGVYAAAA PDGSVLALLE DGPQRTKSVV VLRPATL
Length:297
Mass (Da):31,151
Last modified:February 6, 2007 - v1
Checksum:i817D365D6DF6E9FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000518 Genomic DNA Translation: ABL91339.1
RefSeqiWP_011559493.1, NC_008705.1

Genome annotation databases

EnsemblBacteriaiABL91339; ABL91339; Mkms_2141
GeneIDi32418273
KEGGimkm:Mkms_2141

Similar proteinsi

Entry informationi

Entry nameiTRUB_MYCSK
AccessioniPrimary (citable) accession number: A1UET1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 6, 2007
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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