Reviewed, UniProtKB/Swiss-Prot A1UEQ5 (MQO_MYCSK)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	Mkms_2115

Organism

Mycobacterium sp. (strain KMS) [Complete proteome] [HAMAP]

Taxonomic identifier

189918 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	516 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 516	516	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325503

Sequences

	Sequence		Length	Mass (Da)
	A1UEQ5-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: EEC9685C404ACFEF	FASTA	516	56,003
	10 20 30 40 50 60 MSDAQVAKTD VVLVGAGIMS ATLSALIKLL EPNWSITLIE RLDGAAAESS DPWNNAGTGH 70 80 90 100 110 120 SALCELNYTP EGPGGSIDIT KAVHVNEQFQ VSRQFWTYAV ENGVLPDVRN FINPIPHVSF 130 140 150 160 170 180 VSGARNVEYL RARYDALVPN PLFATMEYID DRDEFARRLP FMADKRDFRE PVALNWSQDG 190 200 210 220 230 240 TDIDFGSLSR QLIGYTAQRG MTTLFGHEVR DLDKQSDGSW SVKVVNRRTG AKRKLNAKFV 250 260 270 280 290 300 FVGAGGGALP LLQKAGIEEA KGFGGFPVGG QWLRTGNPEL TARHQAKVYG MPPLGAPPMS 310 320 330 340 350 360 VPHLDTRVIN GKSWLLFGPF AGWSPKFLKQ GKVTDLPFSV KPNNLASMLG VGLTEMGLLK 370 380 390 400 410 420 YLIGQLLLSE ADRVETLRNF APSARDSDWE LDIAGQRVQV IRRKGKGGVL EFGTTVLAAK 430 440 450 460 470 480 DGSIAGLLGA SPGASTAVPA MLDVMERCFG DRYTAWLPKL KEIVPSLGTK LSDEPKLFQE 490 500 510 IWAHGTKVLK LDHPAAGLPV AGTDTEHREP ATTVTA

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. KMS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000518 Genomic DNA. Translation: ABL91313.1.
RefSeq	YP_938103.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4613474.
GenomeReviews	Gene locus Mkms_2115 in contig CP000518_GR.
KEGG	mkm:Mkms_2115.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A1UEQ5. HLAKAYG.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_MYCSK

Accession

Primary (citable) accession number: A1UEQ5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	February 6, 2007
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)