A1UED6 (A1UED6_MYCSK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
RNAse III EMBL ABL91194.1
EC=3.1.26.3 EMBL ABL91194.1

Gene names

Ordered Locus Names:

Mkms_1995

Organism

Mycobacterium sp. (strain KMS) [Complete proteome] [HAMAP]

Taxonomic identifier

189918 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. SAAS SAAS011907
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. SAAS SAAS011907
Subcellular location	Cytoplasm By similarity SAAS SAAS011907.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. SAAS SAAS011907 Contains 1 RNase III domain. SAAS SAAS011907

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS011907
Ligand	RNA-binding SAAS SAAS011907
Molecular function	Endonuclease SAAS SAAS011907 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA processing Inferred from electronic annotation. Source: InterPro rRNA catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1UED6 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 3B06D57F11B4FD4E	FASTA	234	24,665
	10 20 30 40 50 60 MTLDRSPLLA ALGVTLPDDL LTIALTHRSY SYEHGGLPTN ERLEFLGDSV LGLTITEELF 70 80 90 100 110 120 HRHPDRSEGD LAKLRASIVN TGALADVGRK LSDDGLGSYL LLGKGEESSG GADKSSILAD 130 140 150 160 170 180 GVESLLGAIY VQHGLTVTRE VILRLFAGLL DTAPTLGAGL DWKSSLQELT AARGLGAPHY 190 200 210 220 230 VVTSTGPDHD KEFTATVLVT DIEYGRGVGR TKKEAELKAA AAAWTALSAT DVDA

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. KMS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KMS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000518 Genomic DNA. Translation: ABL91194.1.
RefSeq	YP_937984.1. NC_008705.1.
3D structure databases
ProteinModelPortal	A1UED6.
SMR	A1UED6. Positions 5-155.
ModBase	Search...
Protein-protein interaction databases
STRING	A1UED6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000053166; EBMYCP00000051390; EBMYCG00000053161.
GeneID	4613561.
GenomeReviews	Gene locus Mkms_1995 in contig CP000518_GR.
KEGG	mkm:Mkms_1995.
PATRIC	18102908. VBIMycSp70743_2496.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0571.
GeneTree	EBGT00050000017732.
HOGENOM	HBG744556.
OMA	ALTHKSF.
ProtClustDB	PRK00102.
Family and domain databases
HAMAP	MF_00104. RNase_III. [Tree]
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
KO	K03685.
PANTHER	PTHR11207. PTHR11207. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
SUPFAM	SSF69065. RNase_III. 1 hit.
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1UED6_MYCSK

Accession

Primary (citable) accession number: A1UED6

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)