A1UC23 (GCP_MYCSK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	Mkms_1168

Organism

Mycobacterium sp. (strain KMS) [Complete proteome] [HAMAP]

Taxonomic identifier

189918 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 340	340	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303433

Sequences

	Sequence		Length	Mass (Da)
	A1UC23 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 25EA00D3F5A2DC06	FASTA	340	34,894
	10 20 30 40 50 60 MIILAIESSC DETGVGIAEL SEDGTVTLLA DEVASSVDEH ARFGGVVPEI ASRAHLEALG 70 80 90 100 110 120 PTMRRALDTA GVGRPDVVAA TIGPGLAGAL LVGVAAAKAY SAAWQVPFYG VNHLGGHLAA 130 140 150 160 170 180 DVYDHGPLPE SVGLLVSGGH THLLHVRSLG EPIIELGSTV DDAAGEAYDK VARLLGLGYP 190 200 210 220 230 240 GGKVLDDLAR QGDREAIVFP RGMTGPRDDP FAFSFSGLKT AVARYVESHP EASQADVAAG 250 260 270 280 290 300 FQEAVADVLT RKAVRAAETL GVSTLLIAGG VAANSRLREL AEQRCAESGL TLRIPRPRLC 310 320 330 340 TDNGAMIASF AAHLIAAGAP PSPLEAASDP GLPVVRSQVA

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. KMS." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KMS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000518 Genomic DNA. Translation: ABL90381.1.
RefSeq	YP_937171.1. NC_008705.1.
3D structure databases
ProteinModelPortal	A1UC23.
ModBase	Search...
Protein-protein interaction databases
STRING	A1UC23.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000055768; EBMYCP00000053992; EBMYCG00000055763.
GeneID	4614546.
GenomeReviews	Gene locus Mkms_1168 in contig CP000518_GR.
KEGG	mkm:Mkms_1168.
PATRIC	18101279. VBIMycSp70743_1686.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
GeneTree	EBGT00050000017447.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	MSP189918:MKMS_1168-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCSK

Accession

Primary (citable) accession number: A1UC23

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program