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Protein

Superoxide dismutase [Cu-Zn]

Gene

Mkms_0584

Organism
Mycobacterium sp. (strain KMS)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciMSP189918:GH4X-588-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mkms_0584Imported
OrganismiMycobacterium sp. (strain KMS)Imported
Taxonomic identifieri189918 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
ProteomesiUP000000638 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliA1UAE2.
SMRiA1UAE2. Positions 57-227.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263448.
KOiK04565.
OMAiYNQTNGT.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1UAE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFAVPALALS ACSPNEPVSS EPGTTPSVWT GSPSPSAAPG QGEEGGSGSE
60 70 80 90 100
GQGEGGQKLT AELKSPDGTT VANAEFDFSG GYATVTVQTV ASGQLEPGFH
110 120 130 140 150
GMHVHQVGKC EPNSVAPSGG APGNFNSAGG HFQTEGKTGH PASGDLTSLQ
160 170 180 190 200
VREDGSAMVV TTTDAFTAED LTGGEGTAII IHEKADNFAN IPPEKYNQVN
210 220
GTPGPDQATM ATGDAGGRVA CGVIRSGQ
Length:228
Mass (Da):22,699
Last modified:February 6, 2007 - v1
Checksum:i4D2BE23CD35E42EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000518 Genomic DNA. Translation: ABL89800.1.
RefSeqiWP_011557998.1. NC_008705.1.
YP_936590.1. NC_008705.1.

Genome annotation databases

EnsemblBacteriaiABL89800; ABL89800; Mkms_0584.
KEGGimkm:Mkms_0584.
PATRICi18100124. VBIMycSp70743_1113.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000518 Genomic DNA. Translation: ABL89800.1.
RefSeqiWP_011557998.1. NC_008705.1.
YP_936590.1. NC_008705.1.

3D structure databases

ProteinModelPortaliA1UAE2.
SMRiA1UAE2. Positions 57-227.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL89800; ABL89800; Mkms_0584.
KEGGimkm:Mkms_0584.
PATRICi18100124. VBIMycSp70743_1113.

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263448.
KOiK04565.
OMAiYNQTNGT.
OrthoDBiEOG6K13RS.

Enzyme and pathway databases

BioCyciMSP189918:GH4X-588-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KMSImported.

Entry informationi

Entry nameiA1UAE2_MYCSK
AccessioniPrimary (citable) accession number: A1UAE2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 24, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.