A1UAE2 (A1UAE2_MYCSK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn] RuleBase RU000393
EC=1.15.1.1 RuleBase RU000393

Gene names

Ordered Locus Names:

Mkms_0584 EMBL ABL89800.1

Organism

Mycobacterium sp. (strain KMS) [Complete proteome] [HAMAP] EMBL ABL89800.1

Taxonomic identifier

189918 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000393
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000393
Cofactor	Binds 1 copper ion per subunit By similarity. RuleBase RU000393 Binds 1 zinc ion per subunit By similarity. RuleBase RU000393
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family. RuleBase RU000393

Ontologies

Keywords
Ligand	Copper RuleBase RU000393 Metal-binding RuleBase RU000393 Zinc RuleBase RU000393
Molecular function	Oxidoreductase RuleBase RU000393
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1UAE2 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 4D2BE23CD35E42EE	FASTA	228	22,699
	10 20 30 40 50 60 MFAVPALALS ACSPNEPVSS EPGTTPSVWT GSPSPSAAPG QGEEGGSGSE GQGEGGQKLT 70 80 90 100 110 120 AELKSPDGTT VANAEFDFSG GYATVTVQTV ASGQLEPGFH GMHVHQVGKC EPNSVAPSGG 130 140 150 160 170 180 APGNFNSAGG HFQTEGKTGH PASGDLTSLQ VREDGSAMVV TTTDAFTAED LTGGEGTAII 190 200 210 220 IHEKADNFAN IPPEKYNQVN GTPGPDQATM ATGDAGGRVA CGVIRSGQ

References

[1]

"Complete sequence of chromosome of Mycobacterium sp. KMS." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KMS EMBL ABL89800.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000518 Genomic DNA. Translation: ABL89800.1.
RefSeq	YP_936590.1. NC_008705.1.
3D structure databases
ProteinModelPortal	A1UAE2.
SMR	A1UAE2. Positions 57-227.
ModBase	Search...
Protein-protein interaction databases
STRING	189918.Mkms_0584.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABL89800; ABL89800; Mkms_0584.
GeneID	4614967.
KEGG	mkm:Mkms_0584.
PATRIC	18100124. VBIMycSp70743_1113.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2032.
HOGENOM	HOG000263448.
KO	K04565.
OMA	YNQTNGT.
ProtClustDB	CLSK790516.
Enzyme and pathway databases
BioCyc	MSP189918:GH4X-641-MONOMER.
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024136. SOD_Cu/Zn. IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit. PTHR10003:SF11. PTHR10003:SF11. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1UAE2_MYCSK

Accession

Primary (citable) accession number: A1UAE2

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)