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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Mycobacterium sp. (strain KMS)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi30 – 378ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMSP189918:GH4X-12-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:Mkms_0012
OrganismiMycobacterium sp. (strain KMS)
Taxonomic identifieri189918 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000638 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380DNA replication and repair protein RecFPRO_1000048544Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000269561.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiEOG6HTP3X.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1U8S3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFVRHLTLTD FRSWARADLE LEPGRTVFVG PNGFGKTNLV EALWYSATLG
60 70 80 90 100
SHRVASDAPL IRVGAPRAVV STIVVNEGRE LAVDLEITTG RANKARLNRS
110 120 130 140 150
PVRSPREVLG VLRAVLFAPE DLALVRGDPG ERRRYLDELA TTRRPSIAGV
160 170 180 190 200
RADYDRVIRQ RTALLKSAAG ARYRGDRSVL ETLDVWDGHL AAHGALLMAA
210 220 230 240 250
RADLVHHLAP EVEKAYQLLA PGSRPAAIRY RTSIDAEDDV SAEYYEAALL
260 270 280 290 300
DAMTRRRDAE LERGVCLVGP HRDDLELRLG DQMAKGYASH GESWSMALSL
310 320 330 340 350
RLAAYELLRT DGSDPVLLLD DVFAELDAAR RRALAEVAAS AEQVLVTAAV
360 370 380
AEDIPADWDA RRIMIRMQDD DDGRVSMVES
Length:380
Mass (Da):41,879
Last modified:February 6, 2007 - v1
Checksum:iF0EE31194BFFA861
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000518 Genomic DNA. Translation: ABL89231.1.
RefSeqiWP_011557432.1. NC_008705.1.

Genome annotation databases

EnsemblBacteriaiABL89231; ABL89231; Mkms_0012.
KEGGimkm:Mkms_0012.
PATRICi18098948. VBIMycSp70743_0529.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000518 Genomic DNA. Translation: ABL89231.1.
RefSeqiWP_011557432.1. NC_008705.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL89231; ABL89231; Mkms_0012.
KEGGimkm:Mkms_0012.
PATRICi18098948. VBIMycSp70743_0529.

Phylogenomic databases

HOGENOMiHOG000269561.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiEOG6HTP3X.

Enzyme and pathway databases

BioCyciMSP189918:GH4X-12-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KMS.

Entry informationi

Entry nameiRECF_MYCSK
AccessioniPrimary (citable) accession number: A1U8S3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: April 13, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.