A1U6P4 (UBIC_MARAV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable chorismate--pyruvate lyase
Short name=CL
Short name=CPL
EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	Maqu_3594

Organism

Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter hydrocarbonoclasticus (strain DSM 11845)) [Complete proteome] [HAMAP]

Taxonomic identifier

351348 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Marinobacter

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity HAMAP MF_01632.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ubiquinone biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000292068
Sites
	Binding site	90	1	Substrate By similarity
	Binding site	128	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1U6P4 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 82C0AE206C4A77E0	FASTA	188	21,422
	10 20 30 40 50 60 MPLKDCDQPP ELSIPPTFWY RSLVAAGLYC PEVHGPARYW LTVEGSFTRA LQQKCQERFH 70 80 90 100 110 120 VEILREGFST PTPEEAKRLN LAPRQLAWVR EVRLCGDGRP WVLARTVIPQ TCLHGHGRRL 130 140 150 160 170 180 RNLGNKPLGA YLFSSPEWQR GPLETGLCKA RSNGHPRLAR RSLFHRGSCA LLVGEYLLPR LYQSPNRG

References

[1]

"Complete sequence of chromosome 1 of Marinobacter aquaeolei VT8." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Edwards K., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700491 / DSM 11845 / VT8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000514 Genomic DNA. Translation: ABM20663.1.
RefSeq	YP_960850.1. NC_008740.1.
3D structure databases
ProteinModelPortal	A1U6P4.
ModBase	Search...
Protein-protein interaction databases
STRING	A1U6P4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4654866.
GenomeReviews	Gene locus Maqu_3594 in contig CP000514_GR.
KEGG	maq:Maqu_3594.
PATRIC	22462562. VBIMarAqu65105_4021.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3161.
HOGENOM	HBG644467.
OMA	TREAVDC.
PhylomeDB	A1U6P4.
Enzyme and pathway databases
BioCyc	MAQU351348:MAQU_3594-MONOMER.
Family and domain databases
HAMAP	MF_01632. UbiC. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
KO	K03181.
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_MARAV

Accession

Primary (citable) accession number: A1U6P4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program