A1U543 (PGK_MARAV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglycerate kinase
EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	Maqu_3038

Organism

Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter hydrocarbonoclasticus (strain DSM 11845)) [Complete proteome] [HAMAP]

Taxonomic identifier

351348 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Marinobacter

Protein attributes

Sequence length	386 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity. HAMAP MF_00145
Subcellular location	Cytoplasm Potential HAMAP MF_00145.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 386	386	Phosphoglycerate kinase HAMAP MF_00145		PRO_1000058012
Regions
	Nucleotide binding	340 – 343	4	ATP By similarity
	Region	21 – 23	3	Substrate binding By similarity
	Region	59 – 62	4	Substrate binding By similarity
Sites
	Binding site	36	1	Substrate By similarity
	Binding site	113	1	Substrate By similarity
	Binding site	146	1	Substrate By similarity
	Binding site	197	1	ATP By similarity
	Binding site	314	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1U543 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: B08CD13B9CDF00E6	FASTA	386	40,549
	10 20 30 40 50 60 MAIKKMTDLN LAGKRVLIRE DLNVPVKDGK VSSDARIRAS LPTIKAAKDA GAKVMLMSHL 70 80 90 100 110 120 GRPEEGVYDE ASSMKPVAEH LGTLLGQEVR LIKDYLDGVE VADGEVVLFE NVRFNKGEKK 130 140 150 160 170 180 DNEELARQYA ALCDIYVMDA FGTAHRAQAS THGVARFAPE ACAGPLLAAE LEALGKALDN 190 200 210 220 230 240 PAKPVVAIVG GSKVSTKLDV LNALEKVCDQ IIVGGGIANT FLAAAGHPVG KSLCEHDLID 250 260 270 280 290 300 TAKDIASRVE IPLPVDVVVA SEFAETATAT TKNISDVSDD DMILDVGPET AGQFAELLKN 310 320 330 340 350 360 AKTILWNGPV GVFEFDQFGN GTKALAQAIA ESDAFSLAGG GDTVAAVDKY GVADKISYIS 370 380 TGGGAFLEFV EGKTLPAVAV LEERGD

References

[1]

"Complete sequence of chromosome 1 of Marinobacter aquaeolei VT8." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Edwards K., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700491 / DSM 11845 / VT8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000514 Genomic DNA. Translation: ABM20112.1.
RefSeq	YP_960299.1. NC_008740.1.
3D structure databases
ProteinModelPortal	A1U543.
SMR	A1U543. Positions 2-385.
ModBase	Search...
Protein-protein interaction databases
STRING	A1U543.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4653568.
GenomeReviews	Gene locus Maqu_3038 in contig CP000514_GR.
KEGG	maq:Maqu_3038.
PATRIC	22461432. VBIMarAqu65105_3458.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0126.
HOGENOM	HBG453500.
OMA	AKPMAAI.
PhylomeDB	A1U543.
Enzyme and pathway databases
BioCyc	MAQU351348:MAQU_3038-MONOMER.
Family and domain databases
HAMAP	MF_00145. Phosphoglyc_kinase. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
KO	K00927.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PIRSF	PIRSF000724. Pgk. 1 hit.
PRINTS	PR00477. PHGLYCKINASE.
SUPFAM	SSF53748. PGK. 1 hit.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_MARAV

Accession

Primary (citable) accession number: A1U543

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program