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A1U3F8

- MURG_MARAV

UniProt

A1U3F8 - MURG_MARAV

Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter hydrocarbonoclasticus (strain DSM 11845))
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotation

    Catalytic activityi

    UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity Source: UniProtKB-EC
    3. undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. lipid glycosylation Source: UniProtKB-HAMAP
    4. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
    5. regulation of cell shape Source: UniProtKB-KW
    6. UDP-N-acetylgalactosamine biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

    Enzyme and pathway databases

    BioCyciMHYD351348:GHYZ-2503-MONOMER.
    UniPathwayiUPA00219.

    Protein family/group databases

    CAZyiGT28. Glycosyltransferase Family 28.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotation (EC:2.4.1.227UniRule annotation)
    Alternative name(s):
    Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
    Gene namesi
    Name:murGUniRule annotation
    Ordered Locus Names:Maqu_2452
    OrganismiMarinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter hydrocarbonoclasticus (strain DSM 11845))
    Taxonomic identifieri351348 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeMarinobacter
    ProteomesiUP000000998: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 363363UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferasePRO_0000315115Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi351348.Maqu_2452.

    Structurei

    3D structure databases

    ProteinModelPortaliA1U3F8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0707.
    HOGENOMiHOG000218321.
    KOiK02563.
    OMAiPFIKDMA.
    OrthoDBiEOG61VZFD.

    Family and domain databases

    HAMAPiMF_00033. MurG.
    InterProiIPR006009. GlcNAc_MurG.
    IPR004276. Glyco_trans_28.
    IPR007235. Glyco_trans_28_C.
    IPR006311. TAT_signal.
    [Graphical view]
    PfamiPF04101. Glyco_tran_28_C. 1 hit.
    PF03033. Glyco_transf_28. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01133. murG. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1U3F8-1 [UniParc]FASTAAdd to Basket

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    MTDSPRRRFL MMAGGTGGHV FPALATARAL QQRGHEVHWL GASGGMEERL    50
    IGDTDIPLSL IHISGLRGKG KLALLLAPFR LMRALGEAYT HLRRIRPDCV 100
    VGMGGFVTGP GGIAAWLMRK PLVIHEQNAI AGMTNRWLTR FSETVLEAFP 150
    GSFGDQTVTR CTGNPVRGEV ASMDEPEQRL AGRSGKLRVL VVGGSLGAQV 200
    FNQQLPQALA LMPEADRPDV RHQCGEKNLE AAQAAYEEAG VNASVEPFIR 250
    DMAEAYGWAD LVICRAGALT VSELCAAGIG AILVPFPHAV DDHQTRNGQH 300
    MVKAGAAILV PQPRLTPEVL AETLKDLATD RKRILTMAKA ARSLARPDAT 350
    ERVVNYCLEA ANG 363
    Length:363
    Mass (Da):39,029
    Last modified:February 6, 2007 - v1
    Checksum:i6C0C926CF47BEB0B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000514 Genomic DNA. Translation: ABM19527.1.
    RefSeqiYP_959714.1. NC_008740.1.

    Genome annotation databases

    EnsemblBacteriaiABM19527; ABM19527; Maqu_2452.
    GeneIDi4656931.
    KEGGimaq:Maqu_2452.
    PATRICi22460246. VBIMarAqu65105_2872.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000514 Genomic DNA. Translation: ABM19527.1 .
    RefSeqi YP_959714.1. NC_008740.1.

    3D structure databases

    ProteinModelPortali A1U3F8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 351348.Maqu_2452.

    Protein family/group databases

    CAZyi GT28. Glycosyltransferase Family 28.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABM19527 ; ABM19527 ; Maqu_2452 .
    GeneIDi 4656931.
    KEGGi maq:Maqu_2452.
    PATRICi 22460246. VBIMarAqu65105_2872.

    Phylogenomic databases

    eggNOGi COG0707.
    HOGENOMi HOG000218321.
    KOi K02563.
    OMAi PFIKDMA.
    OrthoDBi EOG61VZFD.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci MHYD351348:GHYZ-2503-MONOMER.

    Family and domain databases

    HAMAPi MF_00033. MurG.
    InterProi IPR006009. GlcNAc_MurG.
    IPR004276. Glyco_trans_28.
    IPR007235. Glyco_trans_28_C.
    IPR006311. TAT_signal.
    [Graphical view ]
    Pfami PF04101. Glyco_tran_28_C. 1 hit.
    PF03033. Glyco_transf_28. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01133. murG. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Marinobacter aquaeolei VT8."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.
      , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Edwards K., Richardson P.
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700491 / DSM 11845 / VT8.

    Entry informationi

    Entry nameiMURG_MARAV
    AccessioniPrimary (citable) accession number: A1U3F8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3