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A1U2B1

- A1U2B1_MARHV

UniProt

A1U2B1 - A1U2B1_MARHV

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Protein
Submitted name:

L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase

Gene

Maqu_2049

Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei785 – 7851UniRule annotation
Active sitei819 – 8191UniRule annotation

GO - Molecular functioni

  1. 1-pyrroline-5-carboxylate dehydrogenase activity Source: InterPro
  2. oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Source: InterPro
  3. proline dehydrogenase activity Source: UniProtKB-EC
  4. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. proline biosynthetic process Source: InterPro
  2. proline catabolic process to glutamate Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciMHYD351348:GHYZ-2096-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenaseImported (EC:1.2.1.88Imported, EC:1.5.99.8Imported)
Gene namesi
Ordered Locus Names:Maqu_2049Imported
OrganismiMarinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)Imported
Taxonomic identifieri351348 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeMarinobacter
ProteomesiUP000000998: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi351348.Maqu_2049.

Structurei

3D structure databases

ProteinModelPortaliA1U2B1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0506.
HOGENOMiHOG000253911.
KOiK13821.
OMAiAGIEKHI.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di1.10.2060.10. 1 hit.
1.20.5.550. 1 hit.
3.20.20.220. 1 hit.
3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR025703. Bifunct_PutA.
IPR005933. Delta1-pyrroline-5-COlate_DH-3.
IPR029041. FAD-linked_oxidoreductase-like.
IPR024090. PRODH_PutA_dom_I.
IPR024089. PRODH_PutA_dom_I/II.
IPR024082. PRODH_PutA_dom_II.
IPR002872. Proline_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
PF01619. Pro_dh. 1 hit.
PF14850. Pro_dh-DNA_bdg. 1 hit.
[Graphical view]
PIRSFiPIRSF000197. Bifunct_PutA. 1 hit.
SUPFAMiSSF51730. SSF51730. 1 hit.
SSF53720. SSF53720. 1 hit.
SSF81935. SSF81935. 1 hit.
TIGRFAMsiTIGR01238. D1pyr5carbox3. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1U2B1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLQQSVAPE LNDIRQAIRA NYLADEHEVI HRLIAEAQLS DETRKAISAR
60 70 80 90 100
AAELVRDVRN SARPTIMEKF LAEYGLTTKE GVALMCLAEA LLRVPDNLTI
110 120 130 140 150
QDLIEDKITS GNWGAHVGKA KSGMINSATL ALLMTSNLLK DSERQSVGDT
160 170 180 190 200
LRKLVKRLGE PVVRTVAGQA MKEMGRQFVL GRTIEEAQDR GKSQEERGYT
210 220 230 240 250
YSYDMLGEAA RTDADAQRYY QAYSDAIDSI SKRCKGDVRT NPGISVKLSA
260 270 280 290 300
LLARYEYGHK ERVMNELMPR ALKLARKAAA ANMGFNIDAE EQDRLDLSLD
310 320 330 340 350
VIEAILSDPE LKDWQGFGVV VQAFGKRASQ TLDWLYALSE KLDRRIMVRL
360 370 380 390 400
VKGAYWDAEI KRAQVMGLSD FPVFTRKACS DVAYLAGARK LLGMTDRIYP
410 420 430 440 450
QFATHNAHSV SAVLELAKDL SRDKFEFQRL HGMGESLHDQ VLEDSGVPCR
460 470 480 490 500
IYAPVGAHKD LLAYLVRRLL ENGANSSFVN QIVDTSITPE EIAKDPIDVV
510 520 530 540 550
VGLGHNLSSK AIVHPSKIFG EQRRNSKGWD ITDPVTVAEI DEGRNRYKSH
560 570 580 590 600
QWKGGPILAV DSVSDEVVEV RNPANPDDLV GHITYTSEAD ISSALGAAQE
610 620 630 640 650
GFKQWSAVPA EERAAMIRRV GDLYEENVHE LFALTTREAG KSLLDAVAEI
660 670 680 690 700
REAVDFAMFY ANEGIRYKND GEARGVMCCI SPWNFPLAIF TGQILANLAA
710 720 730 740 750
GNAVVAKPAE QTSLLAFRAV ELMHQAGIPR AAIQLLPGTG ATVGSGLTSD
760 770 780 790 800
ARVTGVCFTG STATAQRINK AMTEHMEPDA PLVAETGGLN AMIVDSTALP
810 820 830 840 850
EQVVRDVLAS SFQSAGQRCS ALRMLYVQKD IADNLLEMLY GAMEELGIGD
860 870 880 890 900
PWQLSTDVGP VIDENARKKI TDHCQKFEQQ GKLLKKLNVP EKGLFVSPAV
910 920 930 940 950
LQVSGIEELE EEIFGPVLHV ATFEAKDIDK VIDAVNAKGY GLTFGIHSRV
960 970 980 990 1000
DRRIEHIASR IKVGNTYVNR NQIGAIVGSQ PFGGEGLSGT GPKAGGPQYV
1010 1020 1030 1040 1050
RRFLRGEVVE KPAQSSDKVL SADKAQKLID KLAKVEVPEA EGRQALLVPF
1060 1070 1080 1090 1100
FGKVPAPLDE GYEDMPGPTG EQNHLSCHGR GLVLCLGPDA ESAVEQAGTA
1110 1120 1130 1140 1150
LSQGNKVVVI APGAEKALAD AIKAGLPVVA SDGMLDPDAL SHLTGFEAVV
1160 1170 1180 1190 1200
SVAEKPLLKQ YRMALSKRDG ALLPVITEHK LDQRYVIERH LCIDTTAAGG

NASLIASAE
Length:1,209
Mass (Da):131,510
Last modified:February 6, 2007 - v1
Checksum:i03C0386A35B68B11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000514 Genomic DNA. Translation: ABM19130.1.
RefSeqiWP_011785523.1. NC_008740.1.
YP_959317.1. NC_008740.1.

Genome annotation databases

EnsemblBacteriaiABM19130; ABM19130; Maqu_2049.
GeneIDi4657182.
KEGGimaq:Maqu_2049.
PATRICi22459422. VBIMarAqu65105_2464.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000514 Genomic DNA. Translation: ABM19130.1 .
RefSeqi WP_011785523.1. NC_008740.1.
YP_959317.1. NC_008740.1.

3D structure databases

ProteinModelPortali A1U2B1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 351348.Maqu_2049.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM19130 ; ABM19130 ; Maqu_2049 .
GeneIDi 4657182.
KEGGi maq:Maqu_2049.
PATRICi 22459422. VBIMarAqu65105_2464.

Phylogenomic databases

eggNOGi COG0506.
HOGENOMi HOG000253911.
KOi K13821.
OMAi AGIEKHI.
OrthoDBi EOG6BS8QW.

Enzyme and pathway databases

BioCyci MHYD351348:GHYZ-2096-MONOMER.

Family and domain databases

Gene3Di 1.10.2060.10. 1 hit.
1.20.5.550. 1 hit.
3.20.20.220. 1 hit.
3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR025703. Bifunct_PutA.
IPR005933. Delta1-pyrroline-5-COlate_DH-3.
IPR029041. FAD-linked_oxidoreductase-like.
IPR024090. PRODH_PutA_dom_I.
IPR024089. PRODH_PutA_dom_I/II.
IPR024082. PRODH_PutA_dom_II.
IPR002872. Proline_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
PF01619. Pro_dh. 1 hit.
PF14850. Pro_dh-DNA_bdg. 1 hit.
[Graphical view ]
PIRSFi PIRSF000197. Bifunct_PutA. 1 hit.
SUPFAMi SSF51730. SSF51730. 1 hit.
SSF53720. SSF53720. 1 hit.
SSF81935. SSF81935. 1 hit.
TIGRFAMsi TIGR01238. D1pyr5carbox3. 1 hit.
PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Marinobacter aquaeolei VT8."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.
    , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Edwards K., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700491 / DSM 11845 / VT8Imported.

Entry informationi

Entry nameiA1U2B1_MARHV
AccessioniPrimary (citable) accession number: A1U2B1
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3