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A1U1Q6 (MASZ_MARAV) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Malate synthase G
EC=2.3.3.9
Gene names
Name:glcB
Ordered Locus Names:Maqu_1843
OrganismMarinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter hydrocarbonoclasticus (strain DSM 11845)) [Complete proteome] [HAMAP]
Taxonomic identifier351348 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Marinobacter ›

Protein attributes

Sequence length726 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP-Rule MF_00641

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP-Rule MF_00641

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily.

Ontologies

Keywords
   Biological processGlyoxylate bypass
Tricarboxylic acid cycle
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 726726Malate synthase G HAMAP-Rule MF_00641
PRO_1000130890

Sites

Active site3401Proton acceptor By similarity
Active site6321Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A1U1Q6 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: C283C1C0799B0F19

FASTA72679,629
        10         20         30         40         50         60 
MTERVQVGGI QIAKNLYDFV NNEAIPGTGI EADKFWAEFD KIVNELAPRN RELLLKRDEI 

        70         80         90        100        110        120 
QEKMDTWNRE HKGQKLDMAE YKAFLKDIGY LVDEPADFKI STSNVDPEIA TMAGPQLVVP 

       130        140        150        160        170        180 
VMNARFALNA ANARWGSLYD ALYGTDAISE ENGAEKGRGY NPVRGAKVIE WARNLLDGSA 

       190        200        210        220        230        240 
PLASGSHKDA AKYYIDGGKL AVKLQNGDVT GLKDESGFVG YTGAADAPTG VLLVKNGMHF 

       250        260        270        280        290        300 
EIQIDASHPI GKDDGAHVKD VLMESALTTI MDCEDSVAAV DADDKVVAYK NWLGLMKGDL 

       310        320        330        340        350        360 
EESFEKGGQM MTRRMNGDRT YTGADGSELT LKGRSLLFVR NVGHLMTNPA ILLKDGSEIP 

       370        380        390        400        410        420 
EGLMDGLVTS LIAIHDLKGD GKFQNSTKGS VYIVKPKQHG PEEVAFTNEF FGRVEDALGL 

       430        440        450        460        470        480 
PRFTLKVGIM DEERRTTVNL KACIHAAKER TVFINTGFLD RTGDEIHTSM ELGPFIRKGP 

       490        500        510        520        530        540 
MKQAAWINAY EQWNVDIGLE AGLSGVAQIG KGMWAMPDLM AGMLEAKIGH PKAGANTAWV 

       550        560        570        580        590        600 
PSPTAATLHA THYHQVNVFD VQKELANRQR ASLDDILTVP VMEDPSSLSA EDIQQELDNN 

       610        620        630        640        650        660 
AQGILGYVVR WIDQGVGCSK VPDINDVGLM EDRATLRISS QLLTNWLYHG ICSEEQIMET 

       670        680        690        700        710        720 
MKRMAAVVDK QNAGDAAYRN MAPNFDDSIA FQAAVDLVLK GREQPAGYTE PLLHAYRQKA 


KAKYGQ

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References

[1]"Complete sequence of chromosome 1 of Marinobacter aquaeolei VT8."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Edwards K., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700491 / DSM 11845 / VT8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000514 Genomic DNA. Translation: ABM18925.1.
RefSeqYP_959112.1. NC_008740.1.

3D structure databases

ProteinModelPortalA1U1Q6.
SMRA1U1Q6. Positions 2-726.
ModBaseSearch...

Protein-protein interaction databases

STRING351348.Maqu_1843.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM18925; ABM18925; Maqu_1843.
GeneID4655277.
KEGGmaq:Maqu_1843.
PATRIC22458986. VBIMarAqu65105_2253.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2225.
HOGENOMHOG000220740.
KOK01638.
OMAVVKPKMH.
ProtClustDBPRK02999.

Enzyme and pathway databases

BioCycMHYD351348:GHYZ-1905-MONOMER.
UniPathwayUPA00703; UER00720.

Family and domain databases

Gene3D2.170.170.11. 2 hits.
HAMAPMF_00641. Malate_synth_G.
InterProIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
PANTHERPTHR21631:SF1. PTHR21631:SF1. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01345. malate_syn_G. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMASZ_MARAV
AccessionPrimary (citable) accession number: A1U1Q6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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