Reviewed, UniProtKB/Swiss-Prot A1U1Q6 (MASZ_MARAV)

Names and origin

Protein names

Recommended name:
    Malate synthase G
    EC=2.3.3.9

Gene names

Name:	glcB
Ordered Locus Names:	Maqu_1843

Organism

Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter hydrocarbonoclasticus (strain DSM 11845)) [Complete proteome] [HAMAP]

Taxonomic identifier

351348 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Marinobacter

Protein attributes

Sequence length	726 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641
Pathway	Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the malate synthase family. GlcB subfamily.

Ontologies

Keywords
Biological process	Glyoxylate bypass Tricarboxylic acid cycle
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate cycle Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	malate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 726	726	Malate synthase G HAMAP MF_00641		PRO_1000130890
Sites
	Active site	340	1	Proton acceptor By similarity
	Active site	632	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1U1Q6-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: C283C1C0799B0F19	FASTA	726	79,629
	10 20 30 40 50 60 MTERVQVGGI QIAKNLYDFV NNEAIPGTGI EADKFWAEFD KIVNELAPRN RELLLKRDEI 70 80 90 100 110 120 QEKMDTWNRE HKGQKLDMAE YKAFLKDIGY LVDEPADFKI STSNVDPEIA TMAGPQLVVP 130 140 150 160 170 180 VMNARFALNA ANARWGSLYD ALYGTDAISE ENGAEKGRGY NPVRGAKVIE WARNLLDGSA 190 200 210 220 230 240 PLASGSHKDA AKYYIDGGKL AVKLQNGDVT GLKDESGFVG YTGAADAPTG VLLVKNGMHF 250 260 270 280 290 300 EIQIDASHPI GKDDGAHVKD VLMESALTTI MDCEDSVAAV DADDKVVAYK NWLGLMKGDL 310 320 330 340 350 360 EESFEKGGQM MTRRMNGDRT YTGADGSELT LKGRSLLFVR NVGHLMTNPA ILLKDGSEIP 370 380 390 400 410 420 EGLMDGLVTS LIAIHDLKGD GKFQNSTKGS VYIVKPKQHG PEEVAFTNEF FGRVEDALGL 430 440 450 460 470 480 PRFTLKVGIM DEERRTTVNL KACIHAAKER TVFINTGFLD RTGDEIHTSM ELGPFIRKGP 490 500 510 520 530 540 MKQAAWINAY EQWNVDIGLE AGLSGVAQIG KGMWAMPDLM AGMLEAKIGH PKAGANTAWV 550 560 570 580 590 600 PSPTAATLHA THYHQVNVFD VQKELANRQR ASLDDILTVP VMEDPSSLSA EDIQQELDNN 610 620 630 640 650 660 AQGILGYVVR WIDQGVGCSK VPDINDVGLM EDRATLRISS QLLTNWLYHG ICSEEQIMET 670 680 690 700 710 720 MKRMAAVVDK QNAGDAAYRN MAPNFDDSIA FQAAVDLVLK GREQPAGYTE PLLHAYRQKA KAKYGQ

References

[1]

"Complete sequence of chromosome 1 of Marinobacter aquaeolei VT8." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Edwards K., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000514 Genomic DNA. Translation: ABM18925.1.
RefSeq	YP_959112.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1U1Q6.
Genome annotation databases
GeneID	4655277.
GenomeReviews	Gene locus Maqu_1843 in contig CP000514_GR.
KEGG	maq:Maqu_1843.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PKMHGPD.
Family and domain databases
HAMAP	MF_00641. [Tree]
InterPro	IPR011076. Malate_synth-like_core. IPR001465. Malate_synthase. IPR006253. Malate_synthG. [Graphical view]
PANTHER	PTHR21631:SF1. Malate_synthase. 1 hit.
Pfam	PF01274. Malate_synthase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01345. malate_syn_G. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MASZ_MARAV

Accession

Primary (citable) accession number: A1U1Q6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)