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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciMHYD351348:GHYZ-1591-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:Maqu_1559
OrganismiMarinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Taxonomic identifieri351348 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeMarinobacter
ProteomesiUP000000998 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 209209N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197109Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351348.Maqu_1559.

Structurei

3D structure databases

ProteinModelPortaliA1U0X4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

A1U0X4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTARVKICGL TRPQDVEAAV ACGADAIGLV FYAPSPRAVD LEQARILAAK
60 70 80 90 100
VPAFVSATGL FVNPERDYVE AVLDAVPLDL LQFHGDESPE FCQSFGRRWI
110 120 130 140 150
KAVRVREPGQ IEQAFADYHQ ASGLLVDAWD PNRYGGTGQS FNWSLIPESR
160 170 180 190 200
PLPLILAGGL SSDNVARAIE QVRPWAVDVS GGVEESKGKK DATKLSQFFK

EVHRVCKTD
Length:209
Mass (Da):22,812
Last modified:February 5, 2007 - v1
Checksum:i3CA572190A4F35B0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000514 Genomic DNA. Translation: ABM18643.1.
RefSeqiWP_011785045.1. NC_008740.1.
YP_958830.1. NC_008740.1.

Genome annotation databases

EnsemblBacteriaiABM18643; ABM18643; Maqu_1559.
KEGGimaq:Maqu_1559.
PATRICi22458396. VBIMarAqu65105_1965.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000514 Genomic DNA. Translation: ABM18643.1.
RefSeqiWP_011785045.1. NC_008740.1.
YP_958830.1. NC_008740.1.

3D structure databases

ProteinModelPortaliA1U0X4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi351348.Maqu_1559.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM18643; ABM18643; Maqu_1559.
KEGGimaq:Maqu_1559.
PATRICi22458396. VBIMarAqu65105_1965.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.
BioCyciMHYD351348:GHYZ-1591-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Marinobacter aquaeolei VT8."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.
    , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Edwards K., Richardson P.
    Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700491 / DSM 11845 / VT8.

Entry informationi

Entry nameiTRPF_MARHV
AccessioniPrimary (citable) accession number: A1U0X4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 27, 2009
Last sequence update: February 5, 2007
Last modified: March 31, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.