Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

D-(-)-3-hydroxybutyrate oligomer hydrolase

Gene

Maqu_0083

Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D--3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.UniRule annotation

Catalytic activityi

(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H2O = 2 (R)-3-hydroxybutanoate.UniRule annotation

Pathwayi: butanoate metabolism

This protein is involved in the pathway butanoate metabolism, which is part of Lipid metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway butanoate metabolism and in Lipid metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei293 – 2931Charge relay systemUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciMHYD351348:GHYZ-84-MONOMER.
UniPathwayiUPA00863.

Names & Taxonomyi

Protein namesi
Recommended name:
D-(-)-3-hydroxybutyrate oligomer hydrolaseUniRule annotation (EC:3.1.1.22UniRule annotation)
Short name:
3HB-oligomer hydrolaseUniRule annotation
Short name:
3HBOHUniRule annotation
Gene namesi
Ordered Locus Names:Maqu_0083
OrganismiMarinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Taxonomic identifieri351348 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeMarinobacter
Proteomesi
  • UP000000998 Componenti: Chromosome

Subcellular locationi

  • Secreted UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121UniRule annotationAdd
BLAST
Chaini22 – 700679D-(-)-3-hydroxybutyrate oligomer hydrolasePRO_5000208712Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi351348.Maqu_0083.

Family & Domainsi

Sequence similaritiesi

Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4106BE1. Bacteria.
ENOG410XSMB. LUCA.
HOGENOMiHOG000263490.
KOiK07518.
OMAiNPEKDWG.
OrthoDBiPOG091H117N.

Family and domain databases

HAMAPiMF_01906. 3HBOH. 1 hit.
InterProiIPR016582. OHBut_olig_hydro_put.
[Graphical view]
PfamiPF10605. 3HBOH. 1 hit.
[Graphical view]
PIRSFiPIRSF011409. HObutyrate_olig_hydrol. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1TWS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRMMLCTLI GAATVTLTAC KKDEVFNSLP DFLVSDVRQF DYDGNTDDLL
60 70 80 90 100
TAGLGPEGLA SATPPAFVDA LNPTPAELRR LAIYNNYRAL VDTAPGGGYG
110 120 130 140 150
SLFGPAVGNA SGRIPGQEFI AMMQVPGATV PVTVMAQVPD SFDPDFPCMV
160 170 180 190 200
TAPSSGSRGI YGAIGTAGEW GLKKGCAVVY TDKGTGTGAH NLATNTAQSV
210 220 230 240 250
NGTLTMEPEE ALFRADLDAQ SRDDFNSQWP DRFAWKHAHS KQNPEADWGR
260 270 280 290 300
HVLQSIEFGF YMLNTLHGRE LGNGETLRTI NPRNTLVIAS SVSNGGGASV
310 320 330 340 350
RAAEQDEKGL IDGVAVSEPN VNPAVDRSFS IRQGNGPALT EHSRSLLDYT
360 370 380 390 400
TALAVYQGCA NQAPGIRDLA PLNGMFNPPA TGQNICHSLF NKGLVSGATK
410 420 430 440 450
DDWALDAQRI LNEDFGVQPE QNLLAPVHFG LAVAQSIAMT YANAYGRAGV
460 470 480 490 500
EDRVCGLSLA ATGSAGAVVP LAPAAEASLF AASNGIPPSA GVNLVYDNAE
510 520 530 540 550
GQPTSLAVSA SPSSSQVDYG LDALLCLRSL AEGRDVVTGE PLEGAQAELH
560 570 580 590 600
EAISRGISAV RASGDLQRKP TVFVTGRADA ILPINHTSRP YVGLNQAVEG
610 620 630 640 650
RHSNLRYYEI LNAHHLDVLN GFPGIGDRYV PLHHYYFQAL DLMWARLTDK
660 670 680 690 700
QPLPPSQVVR TVPRGSLTTP LTLANLPPIQ SEPAEADRIV FTGNQLQIPD
Length:700
Mass (Da):74,222
Last modified:February 6, 2007 - v1
Checksum:iFF517F646F96C11A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000514 Genomic DNA. Translation: ABM17190.1.
RefSeqiWP_011783663.1. NC_008740.1.

Genome annotation databases

EnsemblBacteriaiABM17190; ABM17190; Maqu_0083.
KEGGimaq:Maqu_0083.
PATRICi22455362. VBIMarAqu65105_0480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000514 Genomic DNA. Translation: ABM17190.1.
RefSeqiWP_011783663.1. NC_008740.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi351348.Maqu_0083.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM17190; ABM17190; Maqu_0083.
KEGGimaq:Maqu_0083.
PATRICi22455362. VBIMarAqu65105_0480.

Phylogenomic databases

eggNOGiENOG4106BE1. Bacteria.
ENOG410XSMB. LUCA.
HOGENOMiHOG000263490.
KOiK07518.
OMAiNPEKDWG.
OrthoDBiPOG091H117N.

Enzyme and pathway databases

UniPathwayiUPA00863.
BioCyciMHYD351348:GHYZ-84-MONOMER.

Family and domain databases

HAMAPiMF_01906. 3HBOH. 1 hit.
InterProiIPR016582. OHBut_olig_hydro_put.
[Graphical view]
PfamiPF10605. 3HBOH. 1 hit.
[Graphical view]
PIRSFiPIRSF011409. HObutyrate_olig_hydrol. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiHBOH_MARHV
AccessioniPrimary (citable) accession number: A1TWS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.