Reviewed, UniProtKB/Swiss-Prot A1TUT1 (SYGA_ACIAC)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	Aave_4178

Organism

Acidovorax avenae subsp. citrulli (strain AAC00-1) [Complete proteome] [HAMAP]

Taxonomic identifier

397945 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00254
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 314	314	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_1000047390

Sequences

	Sequence		Length	Mass (Da)
	A1TUT1-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 3988A1D429EE30B2	FASTA	314	35,597
	10 20 30 40 50 60 MLTFQQIILK LQSYWDAQGC ALLQPYDMEV GAGTSHTATF LRALGPEPWK AAYVQPSRRP 70 80 90 100 110 120 KDGRYGENPN RLQHYYQYQV VLKPAPDNIL ELYLGSLEAL GFDLKKNDIR FVEDDWENPT 130 140 150 160 170 180 LGAWGLGWEV WLNGMEVTQF TYFQQVGGID CKPATGEITY GLERLAMYLQ GVDNVYNLAW 190 200 210 220 230 240 TDTLKYGDVY HQNEVEQSTY NFEHSDADFL FTAFAAHEKQ AQYLMGQQLA LPAYEQVLKA 250 260 270 280 290 300 AHSFNLLDAR GAISVTERAA YIGRIRNLAR AVARSYLDSR ARLGFPMAPR AWADEVLADI 310 AKAEQQQSQK KDAA

References

[1]

"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000512 Genomic DNA. Translation: ABM34719.1.
RefSeq	YP_972493.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1TUT1.
Genome annotation databases
GeneID	4667707.
GenomeReviews	Gene locus Aave_4178 in contig CP000512_GR.
KEGG	aav:Aave_4178.
NMPDR	fig|397945.5.peg.3579.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CRRPTDG.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_ACIAC

Accession

Primary (citable) accession number: A1TUT1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)