Reviewed, UniProtKB/Swiss-Prot A1TT64 (PPNK_ACIAC)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase
      Short name=Poly(P)/ATP NAD kinase
    EC=2.7.1.23

Gene names

Name:	ppnK
Ordered Locus Names:	Aave_3601

Organism

Acidovorax avenae subsp. citrulli (strain AAC00-1) [Complete proteome] [HAMAP]

Taxonomic identifier

397945 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 298	298	Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361		PRO_1000005388

Sequences

	Sequence		Length	Mass (Da)
	A1TT64-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 205E97D06A30EF40	FASTA	298	32,443
	10 20 30 40 50 60 MKLRFQRVAL VGKYQAPTSA GMSDSSRDAL DGIARFLANE GCEVALEADT AANTGFTDYP 70 80 90 100 110 120 ALSVERIGLD CDLCLVVGGD GTMLGVGRQL AQYRTPLIGI NQGRLGFITD IPLGEYPTVL 130 140 150 160 170 180 KPMLRGEYEE DLRPLMRARV MRQGQCVFEA LAMNDVVVNR GSTSGMVELR VEVGGHFVSN 190 200 210 220 230 240 QRADGLIIAS PTGSTAYALS AGGPMLHPTI PGWVLAPIAP HTLSNRPIVL SDSMEVAVEV 250 260 270 280 290 VSGRDVSANF DMQSLASLQH GDRILVQRSD YRARFLHPRG WNYFATLRKK LRWNEGGY

References

[1]

"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000512 Genomic DNA. Translation: ABM34152.1.
RefSeq	YP_971926.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1TT64.
Genome annotation databases
GeneID	4666930.
GenomeReviews	Gene locus Aave_3601 in contig CP000512_GR.
KEGG	aav:Aave_3601.
NMPDR	fig|397945.5.peg.3070.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	HECITIK.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK_ACIAC

Accession

Primary (citable) accession number: A1TT64

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)