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A1TT64 (PPNK_ACIAC) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase
Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23
Gene names
Name:ppnK
Ordered Locus Names:Aave_3601
OrganismAcidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli) [Complete proteome] [HAMAP]
Taxonomic identifier397945 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length298 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP MF_00361

Subcellular location

Cytoplasm By similarity HAMAP MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 298298Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
PRO_1000005388

Sequences

Sequence LengthMass (Da)Tools
A1TT64 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 205E97D06A30EF40

FASTA29832,443
        10         20         30         40         50         60 
MKLRFQRVAL VGKYQAPTSA GMSDSSRDAL DGIARFLANE GCEVALEADT AANTGFTDYP 

        70         80         90        100        110        120 
ALSVERIGLD CDLCLVVGGD GTMLGVGRQL AQYRTPLIGI NQGRLGFITD IPLGEYPTVL 

       130        140        150        160        170        180 
KPMLRGEYEE DLRPLMRARV MRQGQCVFEA LAMNDVVVNR GSTSGMVELR VEVGGHFVSN 

       190        200        210        220        230        240 
QRADGLIIAS PTGSTAYALS AGGPMLHPTI PGWVLAPIAP HTLSNRPIVL SDSMEVAVEV 

       250        260        270        280        290 
VSGRDVSANF DMQSLASLQH GDRILVQRSD YRARFLHPRG WNYFATLRKK LRWNEGGY

« Hide

References

[1]"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AAC00-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000512 Genomic DNA. Translation: ABM34152.1.
RefSeqYP_971926.1. NC_008752.1.

3D structure databases

ProteinModelPortalA1TT64.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1TT64.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4666930.
GenomeReviewsGene locus Aave_3601 in contig CP000512_GR.
KEGGaav:Aave_3601.
NMPDRfig|397945.5.peg.3070.
PATRIC20682361. VBIAciCit38535_3650.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHBG713904.
OMAGPILHES.
PhylomeDBA1TT64.
ProtClustDBPRK02155.

Enzyme and pathway databases

BioCycAAVE397945:AAVE_3601-MONOMER.

Family and domain databases

HAMAPMF_00361. NAD_kinase.
[Tree]
InterProIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. polyP/ATP_NADK_prd.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KOK00858.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK_ACIAC
AccessionPrimary (citable) accession number: A1TT64
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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