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A1TRH4 (AROC_ACIAC) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Aave_2995
OrganismAcidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli) [Complete proteome] [HAMAP]
Taxonomic identifier397945 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 365365Chorismate synthase HAMAP MF_00300
PRO_1000022454

Sequences

Sequence LengthMass (Da)Tools
A1TRH4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 5447C2C2BE03C083

FASTA36538,883
        10         20         30         40         50         60 
MSGNTLGTIF AVTNFGESHG PAIGCVIDGC PPGMELAEAD IQAELDRRRP GTSRHVTQRN 

        70         80         90        100        110        120 
EPDAVEILSG VYEGRTTGTP IALLIRNTDQ RSKDYSNIAQ SFRPGHADYT YWHKYGVRDP 

       130        140        150        160        170        180 
RGGGRSSARL TAPTVAAGAV ARKWLQAKYG VELRACMTQL GELEIPFESW DHVPHNPFFA 

       190        200        210        220        230        240 
PVADVARYEE YMDALRKAGD SCGARLRVQA RNVPVGLGEP LYDKLDADIA HAMMGLNAVK 

       250        260        270        280        290        300 
GVEIGAGFAS VAQRGTTHGD SLTPKGFASN NAGGVLGGIS TGQDIEVSLA IKPTSSIISP 

       310        320        330        340        350        360 
RESIDVHGQS TEVVTKGRHD PCVGIRAAPI AEALLAIVLM DHALRHRAQC GDVVQAVAPI 


QASFL

« Hide

References

[1]"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AAC00-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000512 Genomic DNA. Translation: ABM33562.1.
RefSeqYP_971336.1. NC_008752.1.

3D structure databases

ProteinModelPortalA1TRH4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1TRH4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4667473.
GenomeReviewsGene locus Aave_2995 in contig CP000512_GR.
KEGGaav:Aave_2995.
NMPDRfig|397945.5.peg.2549.
PATRIC20681139. VBIAciCit38535_3045.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMASRFTTQR.
PhylomeDBA1TRH4.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycAAVE397945:AAVE_2995-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_ACIAC
AccessionPrimary (citable) accession number: A1TRH4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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