Reviewed, UniProtKB/Swiss-Prot A1TQF3 (GLMM_ACIAC)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Aave_2619

Organism

Acidovorax avenae subsp. citrulli (strain AAC00-1) [Complete proteome] [HAMAP]

Taxonomic identifier

397945 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	444 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 444	444	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000301269
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1TQF3-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 044A7934D870D436	FASTA	444	47,539
	10 20 30 40 50 60 MARKYFGTDG IRGTVGQAPI TPDFVLRLAH AVGRVLRRTE ERPTVLIGKD TRISGYMLES 70 80 90 100 110 120 ALESGFNSAG VDVVLLGPLP TPGVAYLTRA QRASLGVVIS ASHNAYPDNG IKFFSAQGTK 130 140 150 160 170 180 LPDEWELAVE AALDEAPAWA DSASLGKARR LEDAAGRYIE FCKSTFSQDL TLKGTKIVVD 190 200 210 220 230 240 AAHGAAYHIA PKVFHELGAE VLAIGCSPDG LNINHQVGAT HPDALVRAVR ANRADYGVAL 250 260 270 280 290 300 DGDADRLQMV DAAGRLYNGD ELLYLLAADR LSRGENVPGV VGTLMTNMAV ELALKADGVE 310 320 330 340 350 360 LVRAKVGDRY VLEELARRRW LLGGESSGHL LALDRHTTGD GLISALQVLQ ACVRGGRSLA 370 380 390 400 410 420 RTLEHVRLFP QVLVNVRLLP GQDWKANTVL QDALKSVEAE LGTQGRVLVR ASGTEPLLRV 430 440 MVETSDADRA SHFAHQLADA ARAG

References

[1]

"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000512 Genomic DNA. Translation: ABM33191.1.
RefSeq	YP_970965.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1TQF3.
Genome annotation databases
GeneID	4666593.
GenomeReviews	Gene locus Aave_2619 in contig CP000512_GR.
KEGG	aav:Aave_2619.
NMPDR	fig|397945.5.peg.2246.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	AHAVGRV.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_ACIAC

Accession

Primary (citable) accession number: A1TQF3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)