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Protein

Isocitrate dehydrogenase [NADP]

Gene

Aave_2572

Organism
Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseImported
Biological processGlyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation
LigandManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciACIT397945:G1G7T-2624-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:Aave_2572Imported
OrganismiAcidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)Imported
Taxonomic identifieri397945 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
Proteomesi
  • UP000002596 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi397945.Aave_2572

Structurei

3D structure databases

ProteinModelPortaliA1TQA6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 415Iso_dhInterPro annotationAdd BLAST385

Phylogenomic databases

eggNOGiENOG4108HMX Bacteria
COG0538 LUCA
HOGENOMiHOG000021113
KOiK00031
OMAiFQQIQTR
OrthoDBiPOG091H01VB

Family and domain databases

InterProiView protein in InterPro
IPR019818 IsoCit/isopropylmalate_DH_CS
IPR004439 Isocitrate_DH_NADP_dimer_prok
IPR024084 IsoPropMal-DH-like_dom
PANTHERiPTHR43504 PTHR43504, 1 hit
PfamiView protein in Pfam
PF00180 Iso_dh, 1 hit
SMARTiView protein in SMART
SM01329 Iso_dh, 1 hit
TIGRFAMsiTIGR00183 prok_nadp_idh, 1 hit
PROSITEiView protein in PROSITE
PS00470 IDH_IMDH, 1 hit

Sequencei

Sequence statusi: Complete.

A1TQA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSYQHIKVP AEGQKITVNA DMSLNVPDQP IIPYIEGDGT GFDITPVMLK
60 70 80 90 100
VVDAAVAKAY GGKRKIHWME VFAGEKSTKV YGPDVWLPEE TLHAVRDYVV
110 120 130 140 150
SIKGPLTTPV GGGIRSLNVA LRQELDLYVC LRPIQYFKGV PSPVKEPEKT
160 170 180 190 200
NMVIFRENSE DIYAGIEFEA ESDKAKKLIK ILQEEFGVKK IRFPETSGIG
210 220 230 240 250
VKPVSKEGTQ RLVRKAIQYA IDNDKPSVTI VHKGNIMKFT EGGFRDWAYD
260 270 280 290 300
LAAREFGAEL IDGGPWMKFK NPRTGKEITV KDSIADAFLQ QILLRPAEYS
310 320 330 340 350
VIATLNLNGD YVSDALAAQV GGIGIAPGAN LSDSVAMFEA THGTAPKYAG
360 370 380 390 400
KDYVNPGSEI LSAEMMLRHM GWTEAADIII SSMEKSILSK KVTYDFARLM
410
EGATQVSCSG FGQVMIDNM
Length:419
Mass (Da):46,009
Last modified:February 6, 2007 - v1
Checksum:i427022FD0E488769
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000512 Genomic DNA Translation: ABM33144.1
RefSeqiWP_011795669.1, NC_008752.1

Genome annotation databases

EnsemblBacteriaiABM33144; ABM33144; Aave_2572
KEGGiaav:Aave_2572

Similar proteinsi

Entry informationi

Entry nameiA1TQA6_ACIAC
AccessioniPrimary (citable) accession number: A1TQA6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health