A1TND2 (TRMD_ACIAC) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 41.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: tRNA (guanine-N(1)-)-methyltransferase EC=2.1.1.228 Alternative name(s): M1G-methyltransferase tRNA [GM37] methyltransferase | ||||
| Gene names |
| ||||
| Organism | Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 397945 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax |
Protein attributes
| Sequence length | 255 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Specifically methylates guanosine-37 in various tRNAs By similarity. HAMAP MF_00605 |
| Catalytic activity | S-adenosyl-L-methionine + guanine(37) in tRNA = S-adenosyl-L-homocysteine + N(1)-methylguanine(37) in tRNA. HAMAP MF_00605 |
| Subunit structure | Homodimer By similarity. HAMAP MF_00605 |
| Subcellular location | Cytoplasm Potential HAMAP MF_00605. |
| Sequence similarities | Belongs to the RNA methyltransferase TrmD family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | tRNA processing |
| Cellular component | Cytoplasm |
| Ligand | S-adenosyl-L-methionine |
| Molecular function | Methyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | RNA binding Inferred from electronic annotation. Source: InterPro tRNA (guanine-N1-)-methyltransferase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 255 | 255 | tRNA (guanine-N(1)-)-methyltransferase HAMAP MF_00605 | PRO_1000006441 | |||||
Regions | |||||||||
| Region | 137 – 142 | 6 | S-adenosyl-L-methionine binding By similarity | ||||||
Sites | |||||||||
| Binding site | 117 | 1 | S-adenosyl-L-methionine; via amide nitrogen By similarity | ||||||
Sequences
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References
| [1] | "Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. Richardson P.Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AAC00-1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000512 Genomic DNA. Translation: ABM32470.1. |
| RefSeq | YP_970244.1. NC_008752.1. |
3D structure databases | |
| ProteinModelPortal | A1TND2. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A1TND2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4669343. |
| GenomeReviews | Gene locus Aave_1886 in contig CP000512_GR. |
| KEGG | aav:Aave_1886. |
| NMPDR | fig|397945.5.peg.1634. |
| PATRIC | 20678896. VBIAciCit38535_1934. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0336. |
| HOGENOM | HBG285805. |
| OMA | VCGRFEG. |
| PhylomeDB | A1TND2. |
| ProtClustDB | PRK00026. |
Enzyme and pathway databases | |
| BioCyc | AAVE397945:AAVE_1886-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00605. TrmD. [Tree] |
| InterPro | IPR016009. tRNA_m1G_MeTrfase. IPR002649. tRNA_m1G_MeTrfase_bac. IPR023148. tRNA_m1G_MeTrfase_C. [Graphical view] |
| Gene3D | G3DSA:1.10.1270.20. tRNA_m1G_MeTrfase_C. 1 hit. |
| KO | K00554. |
| PANTHER | PTHR10056. PTHR10056. 1 hit. |
| Pfam | PF01746. tRNA_m1G_MT. 1 hit. [Graphical view] |
| PIRSF | PIRSF000386. tRNA_mtase. 1 hit. |
| TIGRFAMs | TIGR00088. TrmD. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | TRMD_ACIAC | ||||||||
| Accession | Primary (citable) accession number: A1TND2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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