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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciACIT397945:G1G7T-1155-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:Aave_1149
OrganismiAcidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)
Taxonomic identifieri397945 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
Proteomesi
  • UP000002596 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120381 – 280Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST280

Proteomic databases

PRIDEiA1TLA3

Interactioni

Protein-protein interaction databases

STRINGi397945.Aave_1149

Structurei

3D structure databases

ProteinModelPortaliA1TLA3
SMRiA1TLA3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

A1TLA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALYCIGDIQ GCDAALQRLL DTVDFSPSRD TVYLLGDLVN RGPQSAEVLR
60 70 80 90 100
RCARGGDSLR ALLGNHDLHL LAAAHGARKP SRRDTLAGVL QAPDRDALLD
110 120 130 140 150
WLKRQPLARE HRLAGERLLM VHAGVLPSWT ADATLEHAAE VQARLQGDAL
160 170 180 190 200
PEFLQAMYGN APDRWSDELS GMDRWRAIVN ALTRLRFCTP DGRMDFDSSE
210 220 230 240 250
AADAAPDGLV PWFDAPGRRT RGTLVAFGHW STLGWMNRPD LLALDTGCVW
260 270 280
GGCLSAVRFG ATLAEREHIS VRCEQAQAPG
Length:280
Mass (Da):30,655
Last modified:February 6, 2007 - v1
Checksum:iE7FB964191D55DDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000512 Genomic DNA Translation: ABM31741.1
RefSeqiWP_011794294.1, NC_008752.1

Genome annotation databases

EnsemblBacteriaiABM31741; ABM31741; Aave_1149
KEGGiaav:Aave_1149

Similar proteinsi

Entry informationi

Entry nameiAPAH_ACIAC
AccessioniPrimary (citable) accession number: A1TLA3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health