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A1TKW3 (A1TKW3_ACIAC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110
Gene names
Name:aroB HAMAP MF_00110
Ordered Locus Names:Aave_1003
OrganismAcidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli) [Complete proteome] [HAMAP] EMBL ABM31601.1
Taxonomic identifier397945 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00110
   Cellular componentCytoplasm HAMAP MF_00110
   LigandNAD HAMAP MF_00110
   Molecular functionLyase HAMAP MF_00110 EMBL ABM31601.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A1TKW3 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 564F1A72BCEA548B

FASTA37639,728
        10         20         30         40         50         60 
MAPPVASPAP QAHAGRVEIA LGDRSYGIEI GAGLLGDART YGALPRAARA LIVTNETVAP 

        70         80         90        100        110        120 
LYAEPLRAAL SAHYADVVLA VLPDGEEHKD WPTLNRIFDA LLSHGCDRKT VLFALGGGVV 

       130        140        150        160        170        180 
GDMTGFAAAS YMRGVPFVQV PTTLLAQVDS SVGGKTAINH PLGKNMIGAF YQPQLVVCDL 

       190        200        210        220        230        240 
ATLATLPARE LSAGLAEVIK YGPIADMEFL AWLEDHVEAL RAGDHAALAH AVRRSCEIKA 

       250        260        270        280        290        300 
WVVGQDEREA GLRAILNFGH TFGHAIEAGM GYGVWLHGEG VGAGMVMAAE LSRRLGLVDE 

       310        320        330        340        350        360 
AFTARLRRLV ERAGLPVRGA VLDPADNAGR YLELMRLDKK SEGGEIRFVV IDGPGRAAVR 

       370 
PAPDALVREV IGACCA

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References

[1]"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AAC00-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000512 Genomic DNA. Translation: ABM31601.1.
RefSeqYP_969375.1. NC_008752.1.

3D structure databases

ProteinModelPortalA1TKW3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1TKW3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4667980.
GenomeReviewsGene locus Aave_1003 in contig CP000512_GR.
KEGGaav:Aave_1003.
NMPDRfig|397945.5.peg.872.
PATRIC20677029. VBIAciCit38535_1019.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBA1TKW3.
ProtClustDBPRK00002.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1TKW3_ACIAC
AccessionPrimary (citable) accession number: A1TKW3
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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