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A1TJQ2 (TRPC_ACIAC) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase
Short name=IGPS
EC=4.1.1.48
Gene names
Name:trpC
Ordered Locus Names:Aave_0586
OrganismAcidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli) [Complete proteome] [HAMAP]
Taxonomic identifier397945 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134_B

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134_B

Sequence similarities

Belongs to the TrpC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 266266Indole-3-glycerol phosphate synthase HAMAP MF_00134_B
PRO_1000018429

Sequences

Sequence LengthMass (Da)Tools
A1TJQ2 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: A01AFF4B03DD0B58

FASTA26628,679
        10         20         30         40         50         60 
MSDILNKIVA VKREEIAAAQ KKIPLAAMRA DAESRVLTRD FEGALRAKIA AGQAAVIAEI 

        70         80         90        100        110        120 
KKASPSKGVI RENFIPADIA QSYAEGNGKV SAACLSVLTD RQFFQGQPDY LKQARASCAL 

       130        140        150        160        170        180 
PVLRKDFMVD AYQIYESRAM GADAILLIAA CLEDAQMAEF EAIAHSLGMA ALVEVHDGAE 

       190        200        210        220        230        240 
LDRALKLRTP LVGINNRNLR TFEVSLDTTV SLRKAVPSDR LLVAESGILT PQDVKTLRDA 

       250        260 
DVHAFLVGEA FMRAQEPGAA LAKLFA

« Hide

References

[1]"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AAC00-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000512 Genomic DNA. Translation: ABM31190.1.
RefSeqYP_968964.1. NC_008752.1.

3D structure databases

ProteinModelPortalA1TJQ2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1TJQ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4668141.
GenomeReviewsGene locus Aave_0586 in contig CP000512_GR.
KEGGaav:Aave_0586.
NMPDRfig|397945.5.peg.503.
PATRIC20676187. VBIAciCit38535_0600.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0134.
HOGENOMHBG540956.
OMALEYAVPH.
PhylomeDBA1TJQ2.
ProtClustDBPRK00278.

Enzyme and pathway databases

BioCycAAVE397945:AAVE_0586-MONOMER.

Family and domain databases

HAMAPMF_00134_B. IGPS_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01609.
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPC_ACIAC
AccessionPrimary (citable) accession number: A1TJQ2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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