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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciACIT397945:G1G7T-417-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Aave_0414
OrganismiAcidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)
Taxonomic identifieri397945 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
Proteomesi
  • UP000002596 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000179821 – 569Arginine--tRNA ligaseAdd BLAST569

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi397945.Aave_0414

Structurei

3D structure databases

ProteinModelPortaliA1TJ83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi128 – 138"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A1TJ83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSVKQELLA ALAGELEKLS PGSAGRAAFE SPKVAAHGDF ACTAAMQLAK
60 70 80 90 100
PLKLNPRALG EQLKAALEAT PAFARWVDAI EIAGPGFLNI RLKAAAKQEI
110 120 130 140 150
VREVLSAGDR FGYQKDNGQR VLVEFVSANP TGPLHVGHGR QAALGDAICN
160 170 180 190 200
LFSTQGWSVH REFYYNDAGV QIDTLTKSTQ LRARGFKPGD ECWPTDPENP
210 220 230 240 250
ASKTFYNGDY IQDIANDFLA KKTVKADDRE FTANGDVEDY DNIRQFAVAY
260 270 280 290 300
LRNEQDKDLQ AFNLHFDQYY LESSLYTSGR VEATVNRLVE KGHTYEQDGA
310 320 330 340 350
LWLKSTDYGD DKDRVMRKKD GTYTYFVPDV AYHIAKWERG FAKVVNIQGT
360 370 380 390 400
DHHGTIARVR AGLQAADVGI PQGYPDYVLH TMVRVVKGGK EVKIGKRAGS
410 420 430 440 450
YVTLRDLIEW TSKDAVRFFL LSRKPDTEYT FDVDLAVAQN NDNPVYYVQY
460 470 480 490 500
AHARIQSVLR AWAEAGGGDV ASLKDVDLSA LEGPQAQALM LQLAKYPEML
510 520 530 540 550
TAAAEGEAPH DVTFYLRDLA ASYHSYYDAE RILVDDEAVK RARLALVAAT
560
AQVLHNGLKV LGVDAPARM
Length:569
Mass (Da):62,896
Last modified:February 6, 2007 - v1
Checksum:i5A0F4FADD80424F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000512 Genomic DNA Translation: ABM31021.1
RefSeqiWP_011793597.1, NC_008752.1

Genome annotation databases

EnsemblBacteriaiABM31021; ABM31021; Aave_0414
KEGGiaav:Aave_0414

Similar proteinsi

Entry informationi

Entry nameiSYR_ACIAC
AccessioniPrimary (citable) accession number: A1TJ83
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: February 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome