Reviewed, UniProtKB/Swiss-Prot A1TJ83 (SYR_ACIAC)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	Aave_0414

Organism

Acidovorax avenae subsp. citrulli (strain AAC00-1) [Complete proteome] [HAMAP]

Taxonomic identifier

397945 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	569 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 569	569	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_1000017982
Regions
	Motif	128 – 138	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	A1TJ83-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 5A0F4FADD80424F3	FASTA	569	62,896
	10 20 30 40 50 60 MLSVKQELLA ALAGELEKLS PGSAGRAAFE SPKVAAHGDF ACTAAMQLAK PLKLNPRALG 70 80 90 100 110 120 EQLKAALEAT PAFARWVDAI EIAGPGFLNI RLKAAAKQEI VREVLSAGDR FGYQKDNGQR 130 140 150 160 170 180 VLVEFVSANP TGPLHVGHGR QAALGDAICN LFSTQGWSVH REFYYNDAGV QIDTLTKSTQ 190 200 210 220 230 240 LRARGFKPGD ECWPTDPENP ASKTFYNGDY IQDIANDFLA KKTVKADDRE FTANGDVEDY 250 260 270 280 290 300 DNIRQFAVAY LRNEQDKDLQ AFNLHFDQYY LESSLYTSGR VEATVNRLVE KGHTYEQDGA 310 320 330 340 350 360 LWLKSTDYGD DKDRVMRKKD GTYTYFVPDV AYHIAKWERG FAKVVNIQGT DHHGTIARVR 370 380 390 400 410 420 AGLQAADVGI PQGYPDYVLH TMVRVVKGGK EVKIGKRAGS YVTLRDLIEW TSKDAVRFFL 430 440 450 460 470 480 LSRKPDTEYT FDVDLAVAQN NDNPVYYVQY AHARIQSVLR AWAEAGGGDV ASLKDVDLSA 490 500 510 520 530 540 LEGPQAQALM LQLAKYPEML TAAAEGEAPH DVTFYLRDLA ASYHSYYDAE RILVDDEAVK 550 560 RARLALVAAT AQVLHNGLKV LGVDAPARM

References

[1]

"Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000512 Genomic DNA. Translation: ABM31021.1.
RefSeq	YP_968795.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1TJ83.
Genome annotation databases
GeneID	4668362.
GenomeReviews	Gene locus Aave_0414 in contig CP000512_GR.
KEGG	aav:Aave_0414.
NMPDR	fig|397945.5.peg.369.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ADHHGYV.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_ACIAC

Accession

Primary (citable) accession number: A1TJ83

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)