A1TGS6 (PATR_MYCVP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative phenylalanine aminotransferase
EC=2.6.1.-

Gene names

Name:	pat
Ordered Locus Names:	Mvan_5611

Organism

Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]

Taxonomic identifier

350058 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May catalyze the transamination reaction in phenylalanine biosynthesis By similarity. HAMAP MF_01513
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01513
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 351	351	Putative phenylalanine aminotransferase HAMAP MF_01513		PRO_1000024502
Amino acid modifications
	Modified residue	215	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1TGS6 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 8EA512952CF55A5D	FASTA	351	37,840
	10 20 30 40 50 60 MSARLRPELA DLPAYAPGKT VPGAIKIASN ETVHGPLPSV RAAIEKAIDG INRYPDNGYV 70 80 90 100 110 120 ELRERLAKHV NFAPEYISVG CGSVSLCQQL IQITSTVGDE VLFGWRSFEI YPLQVRTAGA 130 140 150 160 170 180 TPVQVPLTDH TFDLDAMLAA ITDRTRLIFV CNPNNPTSTV VDPDALARFV EAVPPHIMVV 190 200 210 220 230 240 VDEAYVEYIR DGLAPDSFGL VRAHSNVVVL RTFSKAYGLA GLRIGYAVAD PDIIAALSKV 250 260 270 280 290 300 YVPFTATSVS QAAAIACLDA ADELLERTDA VVAERTRVSA ALREAGYDLP PSQANFVWLP 310 320 330 340 350 LVGRAQQFAA DAANSRVIVR PYGEDGVRVT IAAPHENDAF LGFARGWDGL R

References

[1]

"Complete sequence of Mycobacterium vanbaalenii PYR-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 7251 / PYR-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000511 Genomic DNA. Translation: ABM16376.1.
RefSeq	YP_956382.1. NC_008726.1.
3D structure databases
ProteinModelPortal	A1TGS6.
ModBase	Search...
Protein-protein interaction databases
STRING	A1TGS6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000079317; EBMYCP00000077270; EBMYCG00000079312.
GeneID	4644045.
GenomeReviews	Gene locus Mvan_5611 in contig CP000511_GR.
KEGG	mva:Mvan_5611.
PATRIC	18189652. VBIMycVan31953_5714.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0079.
GeneTree	EBGT00070000031717.
HOGENOM	HBG646350.
OMA	NNTKIVW.
ProtClustDB	PRK03321.
Enzyme and pathway databases
BioCyc	MVAN350058:MVAN_5611-MONOMER.
Family and domain databases
HAMAP	MF_01513. Phe_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR024892. AroT. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PATR_MYCVP

Accession

Primary (citable) accession number: A1TGS6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program