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Protein

Xylose isomerase

Gene

xylA

Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei65UniRule annotation1
Active sitei68UniRule annotation1
Metal bindingi192Magnesium 1UniRule annotation1
Metal bindingi228Magnesium 1UniRule annotation1
Metal bindingi228Magnesium 2UniRule annotation1
Metal bindingi231Magnesium 2UniRule annotation1
Metal bindingi256Magnesium 1UniRule annotation1
Metal bindingi304Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMVAN350058:G1G7S-5378-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Mvan_5294Imported
OrganismiMycobacterium vanbaalenii (strain DSM 7251 / PYR-1)Imported
Taxonomic identifieri350058 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi
  • UP000009159 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi350058.Mvan_5294

Structurei

3D structure databases

ProteinModelPortaliA1TFW5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini52 – 276AP_endonuc_2InterPro annotationAdd BLAST225

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000022596
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013453 XylA_actinobac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02631 xylA_Arthro, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

A1TFW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVLESSRPV PDALSPRRED KFSFGLWTVG WPGVDPFGVA TRPALDAIEA
60 70 80 90 100
VDRLAALGAY GLTFHDDDLF AFGSSDGERR RAIDRLTSAL SANGLVVPMV
110 120 130 140 150
TTNLFTQPVF KDGGFTSNDR AVRRFALRKV LRNLDLAAEL GAQTFVMWGG
160 170 180 190 200
REGGEYDSAK DVQAALERYR EALDVLCQYV IDQGSGIRFA IEPKPNEPRG
210 220 230 240 250
DILLPTVGHA LAFIETLAHP EMVGVNPETG HEQMSGLNFT HGIAQALYSG
260 270 280 290 300
KLFHIDLNGQ RGIKFDQDLV FGHGDLVNAF SLVDLLEHGG PDGGPAYDGP
310 320 330 340 350
RHFDYKPSRT EDAEGVWASA AANMRMYLLL RQRAAAFRAD PDVREAMVAA
360 370 380 390 400
KVAELRKPTL AAGETYADLL NDRSAYEEFD TGAYFGGKGC GFVALHQLAV

EHLMGAR
Length:407
Mass (Da):44,346
Last modified:February 6, 2007 - v1
Checksum:iC0E2CD3933F951C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000511 Genomic DNA Translation: ABM16065.1
RefSeqiWP_011782435.1, NC_008726.1

Genome annotation databases

EnsemblBacteriaiABM16065; ABM16065; Mvan_5294
KEGGimva:Mvan_5294

Similar proteinsi

Entry informationi

Entry nameiA1TFW5_MYCVP
AccessioniPrimary (citable) accession number: A1TFW5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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