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A1TFW5

- A1TFW5_MYCVP

UniProt

A1TFW5 - A1TFW5_MYCVP

Protein

Xylose isomerase

Gene

xylA

Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei65 – 651UniRule annotation
    Active sitei68 – 681UniRule annotation
    Metal bindingi192 – 1921Magnesium 1UniRule annotation
    Metal bindingi228 – 2281Magnesium 1UniRule annotation
    Metal bindingi228 – 2281Magnesium 2UniRule annotation
    Metal bindingi231 – 2311Magnesium 2UniRule annotation
    Metal bindingi256 – 2561Magnesium 1UniRule annotation
    Metal bindingi266 – 2661Magnesium 2UniRule annotation
    Metal bindingi268 – 2681Magnesium 2UniRule annotation
    Metal bindingi304 – 3041Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMVAN350058:GIWR-5343-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotation
    Ordered Locus Names:Mvan_5294Imported
    OrganismiMycobacterium vanbaalenii (strain DSM 7251 / PYR-1)Imported
    Taxonomic identifieri350058 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000009159: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi350058.Mvan_5294.

    Structurei

    3D structure databases

    ProteinModelPortaliA1TFW5.
    SMRiA1TFW5. Positions 18-407.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2115.
    HOGENOMiHOG000022596.
    KOiK01805.
    OMAiFAVMTEV.
    OrthoDBiEOG62NX4R.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013453. XylA_actinobac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1TFW5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTVLESSRPV PDALSPRRED KFSFGLWTVG WPGVDPFGVA TRPALDAIEA    50
    VDRLAALGAY GLTFHDDDLF AFGSSDGERR RAIDRLTSAL SANGLVVPMV 100
    TTNLFTQPVF KDGGFTSNDR AVRRFALRKV LRNLDLAAEL GAQTFVMWGG 150
    REGGEYDSAK DVQAALERYR EALDVLCQYV IDQGSGIRFA IEPKPNEPRG 200
    DILLPTVGHA LAFIETLAHP EMVGVNPETG HEQMSGLNFT HGIAQALYSG 250
    KLFHIDLNGQ RGIKFDQDLV FGHGDLVNAF SLVDLLEHGG PDGGPAYDGP 300
    RHFDYKPSRT EDAEGVWASA AANMRMYLLL RQRAAAFRAD PDVREAMVAA 350
    KVAELRKPTL AAGETYADLL NDRSAYEEFD TGAYFGGKGC GFVALHQLAV 400
    EHLMGAR 407
    Length:407
    Mass (Da):44,346
    Last modified:February 6, 2007 - v1
    Checksum:iC0E2CD3933F951C3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000511 Genomic DNA. Translation: ABM16065.1.
    RefSeqiWP_011782435.1. NC_008726.1.
    YP_956071.1. NC_008726.1.

    Genome annotation databases

    EnsemblBacteriaiABM16065; ABM16065; Mvan_5294.
    GeneIDi4644684.
    KEGGimva:Mvan_5294.
    PATRICi18189001. VBIMycVan31953_5395.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000511 Genomic DNA. Translation: ABM16065.1 .
    RefSeqi WP_011782435.1. NC_008726.1.
    YP_956071.1. NC_008726.1.

    3D structure databases

    ProteinModelPortali A1TFW5.
    SMRi A1TFW5. Positions 18-407.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 350058.Mvan_5294.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABM16065 ; ABM16065 ; Mvan_5294 .
    GeneIDi 4644684.
    KEGGi mva:Mvan_5294.
    PATRICi 18189001. VBIMycVan31953_5395.

    Phylogenomic databases

    eggNOGi COG2115.
    HOGENOMi HOG000022596.
    KOi K01805.
    OMAi FAVMTEV.
    OrthoDBi EOG62NX4R.

    Enzyme and pathway databases

    BioCyci MVAN350058:GIWR-5343-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013453. XylA_actinobac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02631. xylA_Arthro. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 7251 / PYR-1Imported.

    Entry informationi

    Entry nameiA1TFW5_MYCVP
    AccessioniPrimary (citable) accession number: A1TFW5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 6, 2007
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3