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A1TFW5

- A1TFW5_MYCVP

UniProt

A1TFW5 - A1TFW5_MYCVP

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Protein

Xylose isomerase

Gene
xylA, Mvan_5294
Organism
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei65 – 651 By similarityUniRule annotation
Active sitei68 – 681 By similarityUniRule annotation
Metal bindingi192 – 1921Magnesium 1 By similarityUniRule annotation
Metal bindingi228 – 2281Magnesium 1 By similarityUniRule annotation
Metal bindingi228 – 2281Magnesium 2 By similarityUniRule annotation
Metal bindingi231 – 2311Magnesium 2 By similarityUniRule annotation
Metal bindingi256 – 2561Magnesium 1 By similarityUniRule annotation
Metal bindingi266 – 2661Magnesium 2 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 2 By similarityUniRule annotation
Metal bindingi304 – 3041Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciMVAN350058:GIWR-5343-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Mvan_5294Imported
OrganismiMycobacterium vanbaalenii (strain DSM 7251 / PYR-1)Imported
Taxonomic identifieri350058 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000009159: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi350058.Mvan_5294.

Structurei

3D structure databases

ProteinModelPortaliA1TFW5.
SMRiA1TFW5. Positions 18-407.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000022596.
KOiK01805.
OMAiFAVMTEV.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1TFW5-1 [UniParc]FASTAAdd to Basket

« Hide

MTVLESSRPV PDALSPRRED KFSFGLWTVG WPGVDPFGVA TRPALDAIEA    50
VDRLAALGAY GLTFHDDDLF AFGSSDGERR RAIDRLTSAL SANGLVVPMV 100
TTNLFTQPVF KDGGFTSNDR AVRRFALRKV LRNLDLAAEL GAQTFVMWGG 150
REGGEYDSAK DVQAALERYR EALDVLCQYV IDQGSGIRFA IEPKPNEPRG 200
DILLPTVGHA LAFIETLAHP EMVGVNPETG HEQMSGLNFT HGIAQALYSG 250
KLFHIDLNGQ RGIKFDQDLV FGHGDLVNAF SLVDLLEHGG PDGGPAYDGP 300
RHFDYKPSRT EDAEGVWASA AANMRMYLLL RQRAAAFRAD PDVREAMVAA 350
KVAELRKPTL AAGETYADLL NDRSAYEEFD TGAYFGGKGC GFVALHQLAV 400
EHLMGAR 407
Length:407
Mass (Da):44,346
Last modified:February 6, 2007 - v1
Checksum:iC0E2CD3933F951C3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000511 Genomic DNA. Translation: ABM16065.1.
RefSeqiWP_011782435.1. NC_008726.1.
YP_956071.1. NC_008726.1.

Genome annotation databases

EnsemblBacteriaiABM16065; ABM16065; Mvan_5294.
GeneIDi4644684.
KEGGimva:Mvan_5294.
PATRICi18189001. VBIMycVan31953_5395.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000511 Genomic DNA. Translation: ABM16065.1 .
RefSeqi WP_011782435.1. NC_008726.1.
YP_956071.1. NC_008726.1.

3D structure databases

ProteinModelPortali A1TFW5.
SMRi A1TFW5. Positions 18-407.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 350058.Mvan_5294.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM16065 ; ABM16065 ; Mvan_5294 .
GeneIDi 4644684.
KEGGi mva:Mvan_5294.
PATRICi 18189001. VBIMycVan31953_5395.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000022596.
KOi K01805.
OMAi FAVMTEV.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci MVAN350058:GIWR-5343-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02631. xylA_Arthro. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 7251 / PYR-1.

Entry informationi

Entry nameiA1TFW5_MYCVP
AccessioniPrimary (citable) accession number: A1TFW5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: September 3, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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