Reviewed, UniProtKB/Swiss-Prot A1TDE9 (CYSD_MYCVP)

Names and origin

Protein names

Recommended name:
    Sulfate adenylyltransferase subunit 2
    EC=2.7.7.4
Alternative name(s):
    Sulfate adenylate transferase
      Short name=SAT
    ATP-sulfurylase small subunit

Gene names

Name:	cysD
Ordered Locus Names:	Mvan_4423

Organism

Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]

Taxonomic identifier

350058 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	309 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of cysD, the smaller subunit, and cysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 309	309	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000092212

Sequences

	Sequence		Length	Mass (Da)
	A1TDE9-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 1C34134FF7B26E5A	FASTA	309	35,263
	10 20 30 40 50 60 MTATDELTQN AGRYELSHLR ALEAEAIHII REVAAEFERP VLLFSGGKDS IVMLHLAIKA 70 80 90 100 110 120 FRPGRLPFPV MHVDTGHNFE EVLAARDELV AESGVRLVVA KVQDDIDAGR VVETIPSRNP 130 140 150 160 170 180 MQTFTLLRAI RENKFDAAFG GARRDEEKAR AKERVFSFRD EFGQWDPKNQ RPELWNLYNG 190 200 210 220 230 240 RHRKGEHIRA FPLSNWTEFD IWSYIGAEKI KLPSIYYAHQ RKVFERDGML LAVHKHLQPR 250 260 270 280 290 300 KDEPIIEKSV RFRTVGDVTC TGCVESTAAT VSEVIAETAI SRLTERGATR ADDRISEAGM EDRKREGYF

References

[1]

"Complete sequence of Mycobacterium vanbaalenii PYR-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000511 Genomic DNA. Translation: ABM15199.1.
RefSeq	YP_955205.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1TDE9.
Genome annotation databases
GeneID	4649014.
GenomeReviews	Gene locus Mvan_4423 in contig CP000511_GR.
KEGG	mva:Mvan_4423.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NYPEVIQ.
Family and domain databases
HAMAP	MF_00064. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_MYCVP

Accession

Primary (citable) accession number: A1TDE9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)