A1T8T4 (A1T8T4_MYCVP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III, alpha subunit EMBL ABM13584.1
EC=2.7.7.7 EMBL ABM13584.1

Gene names

Ordered Locus Names:

Mvan_2777

Organism

Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) [Complete proteome] [HAMAP]

Taxonomic identifier

350058 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	1182 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1T8T4 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 436F971826504954	FASTA	1,182	128,872
	10 20 30 40 50 60 MSGSFVHLHN HTEYSMLDGA AKVKPMLAEA QRLEMPAIGM TDHGNMFGAS EFYNAATDAG 70 80 90 100 110 120 IKPIIGIEAY IAPASRFETK RVLWGDPSQK SDDVSGGGSY THMTMVAENA TGLRNLFKLS 130 140 150 160 170 180 SLASFEGQLG KWARMDAEII AEHAEGIIAT TGCPSGEVQT RLRLGHDREA LEAAARWREI 190 200 210 220 230 240 FGPENFFLEL MDHGLDIERR VREGLLDIGQ KLGIPPLATN DCHYVTRDAA QNHEALLCIQ 250 260 270 280 290 300 TGKTLSDPNR FKFDGDGYFL KSAAEMRALW DGQVPGACDS TLLIAERVQS YADVWTPKDR 310 320 330 340 350 360 MPIFPVPEGH DQGSWLTHEV MTGLQERRFH GAPVPQEYID RAQYEIKVIC DKGFPAYFLI 370 380 390 400 410 420 VADLINYARS VGIRVGPGRG SAAGSLVAYA MGITNIDPIP HGLLFERFLN PERPSAPDID 430 440 450 460 470 480 IDFDDRRRGE MLRYAANKWG SDRVAQVITF GTIKTKAALK DSARVHYGQP GFAIADRITK 490 500 510 520 530 540 ALPPPIMAKD IPVSGITDPT HERYKEAAEV RALIDTDPDV RTIYETARGL EGLVRNAGVH 550 560 570 580 590 600 ACAVIMSSEP LIDAIPLWKR PQDGAVITGW DYPSCEAIGL LKMDFLGLRN LTIIGDCIEN 610 620 630 640 650 660 IKANRGIDVD LESLTLDDPK AYELLGRGDT LGVFQLDGGP MRDLLRRMQP TEFNDIVAVL 670 680 690 700 710 720 ALYRPGPMGM NAHNDYADRK NGRQAIKPIH PELEEPLKDI LSETYGLIVY QEQIMFIAQK 730 740 750 760 770 780 VASYSMGKAD ALRKAMGKKK LEVLEAEYQG FKEGMTANGF SEKAVKALWD TILPFAGYAF 790 800 810 820 830 840 NKSHAAGYGL VSYWTAYLKA NYPAEYMAGL LTSVGDDKDK AAVYLADCRR LGITVLPPDV 850 860 870 880 890 900 NESVQNFASV GDDIRFGLGA VRNVGANVVS SLVATRKEKG KFADFSDYLN KIDIAACNKK 910 920 930 940 950 960 VTESLVKAGA FDSLGHPRKG LFLVHTDAVD SVLGTKKAEA MGQFDLFGGA DGSGADAGDS 970 980 990 1000 1010 1020 AFTIKVPDEE WEDKHKLALE REMLGLYVSG HPLNGVAHLL AAQVDTQIPA ILDGDVANDT 1030 1040 1050 1060 1070 1080 QVRVGGILAS VNRRVNKNGL PWASAQIEDL TGGIEVLFFP QTYSMFGAEI ADDVVVLVGA 1090 1100 1110 1120 1130 1140 KVAIRDDRIS LIANELVVPD FSSANVNRPV AVSLPTRQCT VDKVTALKQV LARHPGTAQV 1150 1160 1170 1180 HLRLISGERI TTLELDQSLR VTPSSALMGD LKELLGPGCL GG

References

[1]

"Complete sequence of Mycobacterium vanbaalenii PYR-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I.J., Miller C., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 7251 / PYR-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000511 Genomic DNA. Translation: ABM13584.1.
RefSeq	YP_953590.1. NC_008726.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1T8T4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000082350; EBMYCP00000080303; EBMYCG00000082345.
GeneID	4645306.
GenomeReviews	Gene locus Mvan_2777 in contig CP000511_GR.
KEGG	mva:Mvan_2777.
PATRIC	18183821. VBIMycVan31953_2833.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
GeneTree	EBGT00050000016568.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1T8T4_MYCVP

Accession

Primary (citable) accession number: A1T8T4

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)